Background: Hyperproliferation of collagen in the dermis, caused by an aberrant healing response to injury, causes a keloidal scar that extends beyond the original lesion and grows in a pseudotumor pattern, with tissue deformation and a high recurrence rate following excision. The lasing medium of a pulsed dye laser (PDL) is an organic dye dissolved in a solvent. This list includes some of the most often used laser dyes: rhodamine, fluorescein, coumarin, stilbene and umbelliferone. Ethanol, Water, methanol, hexane, glycol and cyclodextrin, as well as cyclohexane are some of the solvents that are employed. Fast discharge flashlamp or external laser with high energy output. The PDL is hypothesized to improve keloids and hypertrophic scars by causing capillary breakdown, which leads to hypoxia and, in turn, changes the production of local collagen.
Objective: This review article aimed to assess the possible efficacy ofpulsed dye laser in managing keloids.
Methods: Pulsed dye, laser, and keloids were all looked for in PubMed, Google scholar, and Science direct. References from relevant literature were also evaluated by the authors, but only the most recent or complete study from June 2008 to May 2021 was included. Due to the lack of sources for translation, documents in languages other than English have been ruled out. Papers that did not fall under the purview of major scientific investigations, such as unpublished manuscripts, oral presentations, conference abstracts, and dissertations, were omitted.
Conclusion: One of the most promising laser treatments for younger hypertrophic scars and keloids has been the 585-nm pulsed dye laser (PDL), which has shown positive outcomes in numerous trials.