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255204

Prognostic Factors of Short-Term Mortality in Spontaneous Bacterial Peritonitis Patients

Article

Last updated: 24 Dec 2024

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Abstract

Introduction: In cirrhotic individuals, spontaneous bacterial peritonitis (SBP) is one of the most frequent side effects. 1-year mortality is up to 50% even with strong prevention, early diagnosis, and effective care. Aim: To analyze prognostic factors of short-term mortality in SBP individuals. Patients and Methods: In our study, 92 SBP patients were involved. Prothrombin time, international normalized ratio (INR), liver enzymes, serum albumin, total bilirubin, complete blood count, and serum creatinine were all evaluated. A sample of ascitic fluid was collected for chemical analysis. Follow up of the patients was done during hospital admission for complications and mortality.  Results: Significantly correlated with mortality were Child score (P=0.02), MELD score (P=0.003), hepatic encephalopathy (P=0.009), and hepatorenal syndrome (P<0.001) in SBP patients. Patients who died had considerably higher WBCs (P=0.003),  serum creatinine levels: basal creatinine (P<0.001), maximum creatinine (P<0.001) and last creatinine (P<0.001), ascitic fluid WBCs (P<0.001) and PMNL count (P<0.001) while platelets (P<0.001), ALT (P<0.001), Serum total bilirubin (P<0.001), ascitic fluid protein(P<0.001) and ascitic fluid albumin (P=0.007) were higher in survivors. Conclusion: In SBP patients, WBCs, serum creatinine, ascitic fluid WBCs  and PMNL count, MELD score, Child-Pugh score, hepatic encephalopathy and hepatorenal syndrome were all strongly linked to mortality.  

DOI

10.21608/ejhm.2022.255204

Keywords

Liver cirrhosis, mortality, Spontaneous Bacterial Peritonitis

Authors

First Name

Amr

Last Name

Ahmed

MiddleName

-

Affiliation

Faculty of Medicine, Sohag University

Email

amr.hamed@med.sohag.edu.eg

City

Sohag

Orcid

-

First Name

Khairy Hammam

Last Name

Morsy

MiddleName

-

Affiliation

-

Email

-

City

-

Orcid

-

First Name

Asmaa Naser

Last Name

Mohammad

MiddleName

-

Affiliation

-

Email

-

City

-

Orcid

-

Volume

88

Article Issue

1

Related Issue

33970

Issue Date

2022-07-01

Receive Date

2022-08-17

Publish Date

2022-07-01

Page Start

4,117

Page End

4,120

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_255204.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=255204

Order

297

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Prognostic Factors of Short-Term Mortality in Spontaneous Bacterial Peritonitis Patients

Details

Type

Article

Created At

22 Jan 2023