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253079

Right Ventricular Diastolic Dysfunction in Young Adults after Mild COVID-19

Article

Last updated: 03 Jan 2025

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Abstract

Background: Myocardial injury is neither limited to the acute Coronavirus disease 2019 nor moderate-to-severe cases. Objectives:  This study aimed to evaluate the relationship between right ventricular diastolic dysfunction and post- Coronavirus disease 2019 cardiovascular sequelae in young adults with mild disease. Patients and Methods: This study recruited 150 young adults (between 18 and 30 years) who were classified into three equal groups: Group A included 50 patients who sustained cardiac symptoms 12 to 14 weeks following mild Coronavirus disease 2019. Group B included 50 patients who did not show cardiac symptoms 12 to 14 weeks following mild Coronavirus disease 2019. Group C included 50 gender-matched healthy subjects of similar ages without previous Coronavirus disease 2019. Each subject underwent a detailed transthoracic echocardiographic study to detect right ventricular diastolic dysfunction by measuring the tricuspid valve E/A ratio, tricuspid deceleration time, tricuspid E/e' ratio and tricuspid e'/a' ratio.  Results: Right ventricular diastolic dysfunction was higher in group A (80% versus 30% versus 0%, p < 0.001). Tricuspid valve e'/a' was lower in group A (0.86 ± 0.2 versus 1.08 ± 0.2 versus 1.44 ± 0.28, p < 0.001) while tricuspid valve E/ e' was higher (6.7 ± 1.1 versus 3.25 ± 3 versus 3.04 ± 0.36, p < 0.001). Post- Coronavirus disease 2019 patients with right ventricular diastolic dysfunction had a higher right ventricular basal diameter, higher right ventricular systolic pressure, lower right ventricular tricuspid annular plane systolic excursion, and lower fractional area change. Conclusions: After recovery from mild Coronavirus disease 2019, some of young adults had right ventricular diastolic dysfunction, which was more prevalent in those with post- Coronavirus disease 2019 cardiac symptoms.  

DOI

10.21608/ejhm.2022.253079

Keywords

COVID-19, Diastolic Dysfunction, Echocardiography, myocardial injury, Right Ventricle, SARS CoV-2

Authors

First Name

Mohamed Saber

Last Name

Hafez

MiddleName

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Affiliation

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Email

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City

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Orcid

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First Name

Islam

Last Name

Bastawy

MiddleName

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Affiliation

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Email

islambastawy@hotmail.com

City

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Orcid

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First Name

Heba

Last Name

Kamel

MiddleName

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Affiliation

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Email

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City

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Orcid

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Volume

88

Article Issue

1

Related Issue

33970

Issue Date

2022-07-01

Receive Date

2022-08-04

Publish Date

2022-07-01

Page Start

3,959

Page End

3,968

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_253079.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=253079

Order

271

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Right Ventricular Diastolic Dysfunction in Young Adults after Mild COVID-19

Details

Type

Article

Created At

22 Jan 2023