Background: Interventional radiology guided by computed tomography (CT) uses minimally invasive techniques to perform medical diagnostics and treatments. Because it is widely available and can be conducted using a wide range of equipment, CT is frequently utilized for interventional image guiding. Objective: This article highlighted for CT-guided interventional radiology procedures, areas and technique. Methods: Google scholar and PubMed were searched using the following keywords: CT-guided interventional radiology and CT scan. The authors also screened references from the relevant literature including all the identified studies and reviews, only the most recent or complete study was included, between June 2002 and December 2020. Conclusion: The use of CT-guided interventions radiology may offer a number of advantages. A high accuracy of instrument placement avoids the damage of vulnerable structures adjacent to the target and high accuracy to perform diagnostic and therapeutic medical procedures. In addition, could reduce the need for verification scans or CT fluoroscopy resulting in less radiation exposure.