Background: The use of closed reduction and percutaneous K-wires, with or without external fixation, is a common surgical solution for patients with an unstable distal radius fracture. Objective: To detect effectiveness of K-wiring as an efficient method for treating distal radius fractures in adults and elderly in Zagazig University Hospitals. Patients and Methods: At Orthopedic Departments of Zagazig University Hospitals, 24 cases with distal radius fractures were treated by percutaneous K-wiring with six months follow-up. Results: Most of the participants met the Mayo wrist score criteria in 13 of the cases where they were evaluated clinically as outstanding. One patient had Sudeck atrophy, seven patients had superficial skin infection, and two patients had stiffness. Conclusion: In adults and the elderly, distal radius fractures can be effectively treated by percutaneous K-wiring. The surgery is safe, has a low rate of complications, and requires only a brief stay in the hospital. By sticking to the fundamental principles and technical features, most of the complications can be avoided.