Background: It has been frequently utilized in liver transplantation surgeries to determine the liver's preoperative computed tomography volumetry (CTV) to avoid issues that may arise from graft size and residual liver volume. Objective: Liver transplantation in Zagazig University Hospitals was studied to determine the accuracy of the estimation of graft size using manual and automated interactive software. Patients and Methods: Eighteen patients; with age range from 21 to 42 years (mean age 30.4 years) and gender distribution of 6 females (33.3%) and 12 males (66.7%). The outpatient clinic of liver transplantation at the National Hepatology and Tropical Medicine Research Institute in Cairo, Egypt, directed all patients to the Radiology Department. All patients had computed tomography volumetry. Results: Differences in graft size between preoperative and actual graft measurements had an average volume of 21.7+33.65 cm³ and between the pre-op and actual graft volumes, the mean difference was 51.96+33.65 cm³ (range 4-131 cm³). Mean estimated graft-to-recipient weight ratio (GRWR) was (1.1±.2) and mean actual GRWR was (1.1±.3). Correlation between estimated GRWR and actual GRWR was statistically significant. A significant association was found between mean preoperative volume and total volume of the graft. The findings were statistically significant. Conclusion: For determining the volume of preoperative grafts, CT volumetry is a reliable method that was found to be highly correlated with the actual graft volume.