Background: Pre-eclampsia (PE) is a multisystem disorder of unknown cause that is unique to human pregnancy.
Objective: This work aimed to evaluate platelet volume and its significance in the prediction of preeclampsia.
Methods: This is a prospective cohort study that was carried out in the Obstetrics and Gynecology Department (High-risk unit) at Zagazig University Hospitals. Sixty high-risk pregnant women were involved during the period from July 2021 to February 2022. Ultrasound scanning was done to evaluate fetal biometric parameters according to fetal morphology and localization of the placenta. The uterine arteries were identified, and the pulsatility index and resistive index were measured bilaterally. Ultrasound examinations were performed by one observer only.
Results: Platelet (PLT) was significantly higher among control and unaffected groups at all times but MPV and PDW were significantly higher among cases at all times. The first, second, third, fourth, and fifth visits were at 12, 14, 16, 18, and 20 weeks gestation respectively
Conclusions Abnormal platelet indices and uterine artery Doppler indices can be considered as an early, economical, and rapid procedure for the assessment of PE.