Background: Posterior spinal surgery is considered one of the most painful surgeries. Erector Spinae Block is likely to produce effective pain management as it causes blockade of the dorsal rami . Objective: This study was conducted to assess the efficacy of ESPB in controlling intraoperative and POP and surgical field during lumbar spine fixation. Patients and methods: A total of 70 cases were enrolled, and they were haphazardly divided into two groups; ESPB group which comprised 35 cases who underwent the blockade technique, and the control group which included the remaining 35 cases that underwent surgery without blockade. The primary outcome was POP, while secondary outcomes involved intraoperative bleeding, and surgeon satisfaction.  Results: No significant differences were detected among both groups concerning patient demographic features. Operative bed bleeding was significantly decreased in the ESPB group. Also, ESPB group expressed lower pain scores during the initial 6 hours after surgery with no difference detected between both studied groups on subsequent assessment. Surgeon satisfaction was significantly better in the ESPB group. Conclusion: ESPB appears to be safe and efficacious technique not only in decreasing POP, but also in improving operative bed bleeding, and surgeon satisfaction.