Beta
ManageSearchChatDiscover
209422

Investigating Alopecia Areata and its Connection to The High-Mobility Group Box 1: Review Article

Article

Last updated: 24 Dec 2024

OverviewSimilar Items

Subjects

-

Tags

-

Abstract

Background: It is a common and reversible hair loss illness known as alopecia areata (AA). Hair loss on the scalp and other regions of the body can begin as a patchy area of full hair loss which may develop to the entire loss of all hair on the body. It is uncertain what causes AA but it is characterized by hair cycle disruption and the presence of mononuclear cell infiltrates in the perifollicular, as well as peribulbar areas.There have been numerous studies that have shown that AA has been linked to various autoimmune illnesses, including vitiligo. Autoimmune disease is becoming more prevalent, and researchers have found a link between chronic inflammation and HMGB1 (high-mobility group box 1). Objective: To evaluate the role of (HMGB1) protein in pathogenesis of AA. Conclusion: HMGB1 is a promising predictor of prognosis and treatment responsiveness in the pathophysiology of alopecia areata

DOI

10.21608/ejhm.2021.209422

Keywords

Alopecia Areata, High-Mobility Group Box 1

Authors

First Name

Asmaa Abd El-Hameed

Last Name

El-Sayed

MiddleName

-

Affiliation

-

Email

abdelhamied74@gmail.com

City

-

Orcid

-

First Name

Afaf Helmy

Last Name

Ghanem

MiddleName

-

Affiliation

-

Email

-

City

-

Orcid

-

First Name

Mohamed Ibrahim

Last Name

El Ghareeb

MiddleName

-

Affiliation

-

Email

-

City

-

Orcid

-

Volume

85

Article Issue

2

Related Issue

28296

Issue Date

2021-10-01

Receive Date

2021-12-15

Publish Date

2021-10-01

Page Start

4,314

Page End

4,316

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 85_Issue 2_Pages 4314-4316.pdf

PDF . 481.7kB

Link

https://ejhm.journals.ekb.eg/article_209422.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=209422

Order

143

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Investigating Alopecia Areata and its Connection to The High-Mobility Group Box 1: Review Article

Details

Type

Article

Created At

22 Jan 2023