Background: Shrimp, Rissoides desmaresti, making a healthy choice for human consumption. Objective: This study aimed to isolate, and identify some natural bioactive marine products from its shell extract, as well as to investigate the biological activity of the seashell extract and the degree of its influence on various microbiological species and laryngeal cancer,, as well as to discover the distribution and relationship between itand marine algae, as the marine food chain.Materials and methods: Squills were gathered, and the varieties of marine algae connected with the organism in the maritime environment were tallied, since they are a major contributor in the marine environment's productivity. Several biologically active marine natural components were extracted, separated, and identified from the organism under research. Results: The findings revealed a seasonal variation in the percentage of marine algae present, which was reflected on diversity in the environment from one season to the next, and indicated the magnitude of the effect of seasonal change on productivity, food availability, and environmental yield. Antimicrobial activity of Rissoides desmaresti shell extract revealed significant differences between groups treated with shell extract (1.5, 2.5, and 5 mg/mL) in comparison with the control group. In addition, the viability of the Hep -2 cell line after treatment with Rissoides desmaresti shell extract was assessed and microscopic examination  revealed   a significant difference between the shell extract-treated groups and the control group. Depending on the dosage or concentration, cell viability decreased in a dose dependent way. The shell extract suppressed the growth of cancer cell line of larynx. Conclusion: The current study revealed that there was seasonal variation in the percentage of marine algae present, which is reflected in the observed species numbers of marine macro algae in the environment of the organism under study and had an impact on marine productivity, food availability, and eco-physiology of Rissoides desmaresti. Shell extract can be employed as an antibacterial, antifungal, and anticancer agent because of several natural bioactive marine compounds from Rissoides desmaresti shell extract.