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199588

Effect of Phototherapy on Serum Calcium and Magnesium Levels in Neonates Receiving Phototherapy for Neonatal Jaundice

Article

Last updated: 03 Jan 2025

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Abstract

Background: Neonatal hyperbilirubinemia is one of the most common newborn entities. Phototherapy has been the therapy of choice for neonates suffering from indirect hyperbilirubinemia. One of the consequences of phototherapy is hypocalcaemia and hypomagnesaemia. Phototherapy leads to inhibition of pineal gland by transcranial illumination resulting in a decline in melatonin level, which leads to increased calcium absorption by bones. Patients and Methods: This study was conducted on 50 full-term jaundiced neonates (23 males & 27 females) received phototherapy for treatment of neonatal indirect hyperbilirubinemia. Cases were selected from those admitted to NICU of Benha University Hospital. Serum calcium, serum magnesium were measured in their blood samples before phototherapy and after 48 hours and at the end of phototherapy. Results: In our study hypocalcemia was assessed as a complication of phototherapy in newborns managed for neonatal hyperbilirubinemia as mean calcium was 8.63 ±1.54 mg/dl pre-phototherapy and was 8.22 ±1.64 mg/dl post-phototherapy. The difference was as statistically significant (p < 0.001). Calcium level was lower after phototherapy. Pre-phototherapy, 12 (24.0%) showed hypocalcemia (< 8 mg/dl) and 38 (76.0%) showed normal calcium (> 8 md/dl). Post-phototherapy, 19 (38.0%) showed hypocalcemia (< 8 mg/dl) and 31 (62.0%) showed normal calcium (> 8 md/dl). The difference was as statistically significant (p = 0.039). Hypocalcemia was higher after phototherapy. Whereas, mean Mg was 2.25 ± 0.32 mg/dl pre-phototherapy and was 2.03 ± 0.38 mg/dl post-phototherapy. The difference was as statistically significant (p < 0.001). Mg level was lower after phototherapy. Pre-phototherapy, 11 (22.0 %) showed hypo and 39 (78.0 %) showed normal. Post-phototherapy, 17 (34.0 %) showed hypo and 33 (66.0 %) showed normal. The difference was as statistically non-significant (p = 0.238). Conclusion: Hypocalcemia is a common complication of phototherapy whereas hypomagnesaemia cannot be considered as a complication of phototherapy.                                                                                                                   

DOI

10.21608/ejhm.2021.199588

Keywords

phototherapy, Hyperbilirubinemia, calcium, Magnesium

Authors

First Name

hibatallah

Last Name

elshenawi

MiddleName

ahmed

Affiliation

pediatics,medicine,benha ,benha ,egypt

Email

heba.elshenawi@gmail.com

City

Tanta

Orcid

-

First Name

Rania E.

Last Name

Abdelatty

MiddleName

-

Affiliation

-

Email

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City

-

Orcid

-

First Name

Eman R.

Last Name

Abdelgawad

MiddleName

-

Affiliation

-

Email

-

City

-

Orcid

-

First Name

Ismail A.

Last Name

Ramadan

MiddleName

-

Affiliation

-

Email

-

City

-

Orcid

-

Volume

85

Article Issue

1

Related Issue

27163

Issue Date

2021-10-01

Receive Date

2021-10-14

Publish Date

2021-10-01

Page Start

3,402

Page End

3,406

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_199588.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=199588

Order

127

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Effect of Phototherapy on Serum Calcium and Magnesium Levels in Neonates Receiving Phototherapy for Neonatal Jaundice

Details

Type

Article

Created At

22 Jan 2023