Background: Female infertility constitutes one of the commonest problems in gynecological practice. Infertility is defined as failure to achieve pregnancy during one year of frequent unprotected intercourse. Objective: This study aimed to evaluate the role of the combined laparoscopy and hysteroscopy in the diagnosis and treatment of infertile female. Patients and methods: This retrospective study was conducted at Gynecologic Endoscopic Unit, Zagazig University Hospital during the period from December 2020 to May 2021. Two hundred infertile women were included in this study. They were divided by the following percent 1:1 primary to secondary infertile cases. Group І: 50% patients with primary infertility and group II included 50% patients with secondary infertility. Women aged 20-40 years with normal hormone profile without male factor infertility were included. Results: The frequency of women with arcuate uterus is significantly increased in group І than in group II. Regarding frequency of women with arcuate uterus, bicornuate and very small uterine cavity were significantly increased in group І than in group II and the frequency of women with intrauterine synechia and bilateral narrow corneal end were significantly higher in group II than in group І. Conclusions: laparoscopy and hysteroscopy play very important  role as diagnostic and therapeutic tools in the infertile women. Combined diagnostic simultaneous laparoscopy and hysteroscopy should be performed in all infertile patients before the treatment.