Background:  Chronic cyclic pelvic pain is cyclic pain located in the pelvis and the lower abdominal area, persisting for 6 months or more with no obvious pathological cause for their pain and severe enough to interfere with daily activities. Objective: This study was conducted to compare the effect of aerobic exercise versus the effect of muscle energy technique on chronic cyclic pelvic pain. Patients and Methods: 30 women complaining of increased pelvic pain of unknown cause lasts more than 6 months diagnosed and referred by their gynecologist. They were divided into two equal groups, Group (A) received muscle energy technique; and Group (B) received aerobic exercise. Both groups were assessed before and after the treatment period (8 weeks) for pain degree by visual analog scale (VAS) and assessment of premenstrual, menstrual, and intermenstrual symptoms by menstrual distress questionnaire scale (MDQ).  Results: The results of this study revealed that there was a significant decrease in VAS and MDQ values post-treatment in both groups (A and B) compared with that pretreatment values, when comparing both groups there was a more significant decrease in the post-treatment values of VAS and MDQ of the group (A) compared with that of the group (B).  Conclusion: It can be concluded that both muscle energy technique and aerobic exercise will improve chronic cyclic pelvic pain but muscle energy technique resulted in better improvement as compared to aerobic exercise on chronic cyclic pelvic pain.