Background: A giant cell tumor of bone (GCTB) is a primary bone tumor with potential invasion, local recurrence, and low probability of distant metastasis. Surgical treatment stills the most effective treatment for this kind of tumor. The surgery often involves defect reconstruction following tumor removal. Objective: Aim of the current work was to evaluate the results of surgical treatment of giant cell tumor in proximal end of tibia by curettage and bone cement. Patients and methods: This study included a total of eighteen adult patients with giant cell tumor of proximal end of tibia, attending at Department of Orthopedic, Zagazig University Hospitals. Patients were treated by curettage and bone cement. This study was conducted between January 2020 to March 2021. Results: In this study the age was (30.39±6.4) years ranged from 22 to 41 years, half of the group (50.0%) had age less than 28 years and the other half were equal or more than 28 years. Two thirds (66.7%) of the studied group were females and one third (33.3%) of them were males(2:1). Concerning campanacci radiological grading of lesion; most of the studied group (83.3%) had campanacci grade I and grade II (16.7%). The functional outcome by the musculoskeletal tumor society functional scoring system (MSTS) in the present study revealed that two thirds (66.7%) of the studied group didn't have pain and only (33.3%) of them had intermediate pain. Conclusion: It could be concluded that patients with GCT of the bone at the proximal end of tibia can be treated satisfactorily with curettage and bone cement packing with lower recurrence rate.  Better MSTS functional results were also observed after extended curettage and bone cement.