Background: Psoriasis is a chronic inflammatory, immune-mediated systemic disease with skin manifestations that typically follow a relapsing and remitting course. The most common form, plaque psoriasis, occurs in ∼80–90% of psoriatic patients.  Objective: The aim of the current work was to evaluate level of serum testosterone in psoriasis male patients and its relation to severity of the disease. Patients and methods: This cohort study included a total of 35 psoriatic patients, attending At Outpatient Clinic, Dermatology and Venereology Department, Zagazig University Hospital, Egypt. This study was conducted between January 2020 to October 2020. Serum free and total testosterone and total cholesterol were measured. Result: About two thirds of the studied group (71.4 %) had normal testosterone level and (28.6 %) had low testosterone level. Conclusion: Low serum total and free testosterone levels in male psoriasis patients are present and they correlate with disease severity.