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180861

Relationship between Plasma Levels of Vitamin D in Pregnant Women and Development of Gestational Diabetes Mellitus

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Last updated: 03 Jan 2025

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Abstract

Background: Gestational diabetes mellitus (GDM) is the leading cause of complications associated with childbirth for both mothers and offspring, and it is considered to be caused by the imbalance between insulin resistance and insulin secretion and contributed maternal hyperglycemia.  This study aimed to assess the relationship between plasma levels of vitamin D in pregnant women and the development of gestational diabetes mellitus. Patients and Methods: A case-control study was conducted at Gynecology and Obstetrics Department, Zagazig University during the period from August 2020 until April 2021. It included a total of 104 pregnant women. Clinical and obstetrical data were gathered, 25(OH) vitamin D3 total level in ng/ml at week gestation (10-12), (24-26), and (34-36). The blood samples were performed by a Cobas 6000. Results: There is a strong correlation between vitamin D deficiency with the occurrence of gestational diabetes with a cut-off value of ≤14.1 at (10-12) weeks gestation, sensitivity 100%, specificity 97.83%, NPV 100%, and PPV 93.3%. Conclusions: There is an inverse association of vitamin D status with gestational diabetes risk.  

DOI

10.21608/ejhm.2021.180861

Keywords

plasma, Vitamin D, gestational diabetes mellitus (GDM)

Authors

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Ali El Shabrawy

Last Name

Ali

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First Name

Wael Sabry

Last Name

Noseir

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First Name

Mohammed El-Hussiny

Last Name

El-Kadosi

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First Name

Raouf Elmahdi Omar

Last Name

Muftah

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Email

raoufelmahdi_86@yahoo.com

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Volume

84

Article Issue

1

Related Issue

25405

Issue Date

2021-07-01

Receive Date

2021-06-29

Publish Date

2021-07-01

Page Start

2,097

Page End

2,102

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_180861.html

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https://ejhm.journals.ekb.eg/service?article_code=180861

Order

74

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Relationship between Plasma Levels of Vitamin D in Pregnant Women and Development of Gestational Diabetes Mellitus

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Article

Created At

22 Jan 2023