Beta
ManageSearchChatDiscover
178601

Comparison between Caudal Dexmedetomidine and Morphine for Postoperative Analgesia in Pediatric Infraumbilical Surgeries

Article

Last updated: 03 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

-

Abstract

Background: The usage of caudal opioids extends the length of analgesia substantially, but it often comes with a slew of adverse side effects, including fatigue, vomiting, pruritus, urinary retention, and a chance of respiratory distress later on.
Objective: The aim of this analysis was to compare the effects of caudal dexmedetomidine versus morphine in conjunction with bupivacaine in pediatric infraumbilical surgeries.
Patients and Methods: This randomized controlled sample involved 90 pediatric patients aged 1 to 7 years old, of American Society of Anesthesiologists (ASA) physical status I-II, of both sexes, who were scheduled for lower abdominal surgeries. Patients were allocated to three equal groups. Group D got a 0.25% bupivacaine + 1 g/kg dexmedetomidine. Group M obtained a 0.25% bupivacaine + 30 g/kg morphine mixture. Group MD: dexmedetomidine 1 g/kg and morphine 30 g/kg with bupivacaine were used in a single dose caudal epidural analgesia.
Results: Intraoperative heart rate, mean arterial blood pressure at 20, 25, 30 and 45 min was significantly decreased in group MD than group D and group M while in postoperative period were insignificantly among the three groups at all times of measurement. FLACC was significantly lower in MD group at discharge, 1, 2, 3, 6, 12 and 18 hours. Ramsey sedation score (RSS) at 30 min was significantly decreased in group M than group D and in group MD than group M. Time for 1st analgesia and paracetamol dosage was significantly earlier in group M than group D and group MD. Pruritus and vomiting were significantly lower in group D than other groups.
Conclusions: The addition of dexmedetomidine to caudal morphine in pediatric patients produced longer postoperative analgesia, more sedation and with better emergence from anesthesia and hemodynamic stability, with fewer side effects than morphine.

DOI

10.21608/ejhm.2021.178601

Keywords

caudal, Dexmedetomidine, morphine, Pediatrics

Authors

First Name

Mohamed Kamal

Last Name

Mahmoud

MiddleName

-

Affiliation

Department of Anesthesia, Intensive Care and Pain Management, Faculty of Medicine, Sohag University, Egypt

Email

mohkamalhegazy@gmail.com

City

-

Orcid

-

First Name

Khaled Abdelfattah Mohamed

Last Name

Abdelfattah

MiddleName

-

Affiliation

Department of Anesthesia, Intensive Care and Pain Management, Faculty of Medicine, Sohag University, Egypt

Email

-

City

-

Orcid

-

First Name

Hamza Aboalm

Last Name

Mahmoud

MiddleName

-

Affiliation

Department of Anesthesia, Intensive Care and Pain Management, Faculty of Medicine, Sohag University, Egypt

Email

-

City

-

Orcid

-

First Name

Ahmed Elsaeed Abd Elrahman

Last Name

Ali

MiddleName

-

Affiliation

Department of Anesthesia, Intensive Care and Pain Management, Faculty of Medicine, Sohag University, Egypt

Email

-

City

-

Orcid

-

Volume

84

Article Issue

1

Related Issue

25405

Issue Date

2021-07-01

Receive Date

2021-06-19

Publish Date

2021-07-01

Page Start

1,901

Page End

1,907

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 84_Issue 1_Pages 1901-1907.pdf

PDF . 498.7kB

Link

https://ejhm.journals.ekb.eg/article_178601.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=178601

Order

43

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Comparison between Caudal Dexmedetomidine and Morphine for Postoperative Analgesia in Pediatric Infraumbilical Surgeries

Details

Type

Article

Created At

22 Jan 2023