Background: Trauma-related deaths are one of the top 10 causes of death. Resuscitation in trauma and critically ill patients are challenging. Clinical and laboratory parameters are used to verify the different measurements. Lactate is a diagnostic and prognostic biomarker in sepsis and trauma.
Objective: The aim of the current work was to investigate lactate clearance in patients admitted to emergency department (ED) and compare with the revised trauma score to predict mortality rate in polytrauma patients. Patients and methods: This prospective case-control study included a total of 200 polytraumatic patients with availability of Blood sampling, admitted to Department of Emergency Medicine, Mansoura University Hospitals. This study was conducted over a period of 12 months. Serum lactate was collected in tubes before receiving any type of treatment. The analysis was performed within 1 h from blood collection and six hours.
Results: Regarding association with mortality, Lactate first hour, Lactate after 6 hours and Lactate clearance demonstrated significant correlation with it (P<0.05), while the remaining factors were not correlated (P>0.05). Regarding association with incidence of discharge for ICU, type of injury and Revised trauma score were correlated with it (P<0.05).
Conclusion: It could be concluded that serum lactate level and lactate clearance could be used as an independent predictor of mortality, incidence of discharge for ICU as well as admission to ICU with comparable efficacy to revised trauma score (RTS) in terms of Triage management.