Background: Platelet-rich plasma PRP is being used as a new therapeutic option for different pathologies in the field of dermatology, such as trichology, wound healing, and cosmetic medicine. Platelet-rich plasma is an exciting new technology that may have the potential to serve as an alternative or adjuvant treatment to surgery in many common injuries/conditions in sports medicine. The growth factors provided by platelets and plasma are essential to the tissue repair process. It could have its effect due to the microenvironment of the tissue. It is used within, the tissue's specific processes for healing, or PRP's possible ability to enchange stem cell proliferation, depending on its preparation, activation, and variable contents. Accordingly, it may be effective treatment for some gynecological and obstetrical conditions. Aim of the work: We conducted this essay to confirm PRP efficacy and safety in varous obstetric and gynecological disorders. Methodology: Relevant citations were extracted from Pubmed, Google scholar, Clinical key, Scopus, Med-line, Embase and Cochrane to identify studies investigating the uses of PRP in gynecology from 2010 to 2020. Conclusion: PRP is an innovative therapeutic modality, as it is affordable, simple, easily performed, and effective. In the field of gynecology, the risks of PRP therapy as infection, bleeding, and nerve damage, appear to be minimal.