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150386

Corneal Elevation Changes in Normal Population and Keratoconus Patients Using Different Acquisition Diameters with Scheimpflug Imager

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Last updated: 30 Jan 2023

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Abstract

Background:     Keratoconus is a bilateral, progressive, noninflammatory disease of the cornea which often leads to high myopia and astigmatism with an estimated prevalence of approximately 1 in 2000. Objective: To detect the changes in corneal elevation values using different acquisition diameters (8, 9 mm) in both normal population and keratoconus patients. Patients and Methods: This is a cross-sectional clinical trial conducted at the Ophthalmology Department, Menoufia University Hospital, and Tiba eye center, Menoufia, Egypt in the period between January 2019 to December 2020. Two hundred corneas of two hundred subjects were involved and categorized into two groups, a control group with normal cornea100 subjects (group A) and a group with keratoconus100 subjects (group B) both confirmed by clinical examination and pentacam readings. Results: Receiver operating curve (ROC) analysis was conducted to identify the optimal elevation front parameters levels for prediction ofkeratoconus. The best cut-off values for front parameters BFS 8mm, BFS 9mm, BFTE 8mm and BFTE 9mm were 6.5, 10.5,2.5,2.5 with (96%,92%,92%,92% sensitivity, and 96%,96%,80%, 72% specificity), respectively. Also, the best cut-off values for back parameters levels for prediction of keratoconus for BFS 8mm, BFS 9mm, BFTE 8mm and BFTE 9mm were 14.0, 25.5, 6.5 and 9.5 mm with (96%, 96%, 80%, 72% sensitivity, and 88%, 96%, 64%, 88% specificity), respectively. Conclusion: We can conclude that there was a significant increase in elevation back parameters in keratoconus patients compared to control. The best cut-off values for front parameters levels as BFS (8, 9mm) and BFTE (8, 9 mm) was 6.5, 10.5, 2.5, and 2.5 mm, respectively.  

DOI

10.21608/ejhm.2021.150386

Keywords

Corneal elevation, BFS, BFTE, Keratoconus, pentacam

Authors

First Name

Sameh Mohamed

Last Name

Elgouhary

MiddleName

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Affiliation

Department of Ophthalmology, Faculty of Medicine, Menoufia University, Menoufia, Egypt

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First Name

Mona Abd Elrahman

Last Name

Abd Elkawi

MiddleName

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Affiliation

Department of Ophthalmology, Faculty of Medicine, Menoufia University, Menoufia, Egypt

Email

dr.monaabdelrahman2021@gmail.com

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Orcid

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First Name

Mohamed Samy

Last Name

Abd Elaziz

MiddleName

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Affiliation

Department of Ophthalmology, Faculty of Medicine, Menoufia University, Menoufia, Egypt

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Volume

82

Article Issue

4

Related Issue

22125

Issue Date

2021-01-01

Receive Date

2021-02-21

Publish Date

2021-01-01

Page Start

609

Page End

614

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_150386.html

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https://ejhm.journals.ekb.eg/service?article_code=150386

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4

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

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Article

Created At

22 Jan 2023