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142881

Study of MICS in Hemodialysis Patients and Its Relation with Serum Thyroid Hormones

Article

Last updated: 03 Jan 2025

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Abstract

Background: Malnutrition-inflammation complex syndrome (MICS) is a frequent and serious problem in patients undergoing dialysis with estimated prevalence about 18–75%. The etiology is multifactorial. MICS is believed to be main cause of erythropoietin hyporesponsiveness, low free triiodothyronine (FT3) and increased mortality and hospitalization among the dialysis patients.
Objective: To determine the prevalence of MICS and identify association between MICS and thyroid hormones. Patients and Methods: This was cross sectional study, which was conducted on 91 patients admitted at Hemodialysis Units of Zagazig University Hospitals and Fakous General Hospital. Blood samples had been obtained before the initiation of the HD session and after an 8 hours fasting, blood measurements included: Serum urea, creatinine, TSH, T3, FT3 and FT4.
Results: This study showed that, prevalence of MICS was about 56%. There was statistically significant difference between patients had MICS and patients without MICS regarding age, and duration of hemodialysis. There was no statistically significant difference between patients had MICS and patients without MICS regarding T3, T4, TSH. There was statistically significant difference between patients had MICS and patients without MICS regarding serum creatinine.
Conclusion: This study concluded high prevalence of malnutrition-inflammation complex syndrome on patients on dialysis. There was no association between MICS and thyroid hormones.

DOI

10.21608/ejhm.2021.142881

Keywords

dialysis, frequency, Malnutrition inflammation complex syndrome, thyroid hormones

Authors

First Name

Mohamed Omar Al Sayed

Last Name

Ali

MiddleName

-

Affiliation

Department of Internal Medicine, Faculty of Medicine – Zagazig University

Email

dr.mohamed2008@gmail.com

City

-

Orcid

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First Name

Mohammed Ali Fahmy

Last Name

El Zanaty

MiddleName

-

Affiliation

Department of Internal Medicine, Faculty of Medicine – Zagazig University

Email

-

City

-

Orcid

-

First Name

Tamer Mohamed

Last Name

Goda

MiddleName

-

Affiliation

Department of Internal Medicine, Faculty of Medicine – Zagazig University

Email

-

City

-

Orcid

-

Volume

82

Article Issue

2

Related Issue

20779

Issue Date

2021-01-01

Receive Date

2021-01-24

Publish Date

2021-01-01

Page Start

237

Page End

240

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 82_Issue 2_Pages 237-240.pdf

PDF . 555.4kB

Link

https://ejhm.journals.ekb.eg/article_142881.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=142881

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Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Study of MICS in Hemodialysis Patients and Its Relation with Serum Thyroid Hormones

Details

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Article

Created At

22 Jan 2023