ManageChatDiscover
137142

The Role of Functional MRI in The Evaluation of The Treated Head and Neck Squamous Cell Carcinoma

Article

Last updated: 03 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

-

Abstract

Background: The diffusion-weighted imaging (DWI) with apparent diffusion coefficient (ADC) map and the dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) constitute the functional MRI technique with many oncological applications as it can define tissue microstructure and characterize the post-treatment changes from a recurrent tumor in treated head and neck squamous cell carcinoma (HNSCC).
Objective: To evaluate the role of the DWI, ADC map and DCE-MRI for characterization of post-treatment changes and recurrent tumors in patients with treated HNSCC.
Patients and Methods: Forty-five patients with treated HNSCC were included in this study with mean ages of 59 ± 7.5 years. The patients underwent pre and post-contrast head and neck MRI, DWI with ADC map and DCE-MRI, each study diagnosis was then compared to the patient outcome.
Results: The sensitivity and specificity of the qualitative DWI (DW-MRI) (87.5% and 82.8% respectively) were higher than the conventional MRI (75% and 75.9% respectively). The ADC cut-off point for the diagnosis of HNSCC recurrence was 1.095 x10-3 mm2/s with sensitivity and specificity of 87.5%, 86.2% respectively. The DCE- MRI revealed a significant difference in the type of time intensity curve (TIC) between post-treatment changes and recurrent lesion (p-value < 0.0001).
Conclusion: The DWI, ADC and the DCE-MRI can be used as a synchronized tool for the differentiation between post-treatment changes and recurrent tumor in treated HNSCC patients.

DOI

10.21608/ejhm.2021.137142

Keywords

HNSCC, MRI, DWI, ADC, DCE-MRI

Authors

First Name

Ahmed S.

Last Name

Abdelrahman

MiddleName

-

Affiliation

Radiology Department – Faculty of Medicine, Ain Shams University, Cairo, Egypt

Email

dr_ahmedsamy@yahoo.com

City

-

Orcid

-

First Name

Amgad S.

Last Name

Abdel-Rahman

MiddleName

-

Affiliation

Radiology Department – Faculty of Medicine, Ain Shams University, Cairo, Egypt

Email

-

City

-

Orcid

-

First Name

Mena E.Y.

Last Name

Ekladious

MiddleName

-

Affiliation

Radiology Department – Faculty of Medicine, Ain Shams University, Cairo, Egypt

Email

-

City

-

Orcid

-

Volume

82

Article Issue

1

Related Issue

20276

Issue Date

2021-01-01

Receive Date

2021-01-08

Publish Date

2021-01-01

Page Start

11

Page End

20

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 82_Issue 1_Pages 11-20.pdf

PDF . 626.4kB

Link

https://ejhm.journals.ekb.eg/article_137142.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=137142

Order

3

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

The Role of Functional MRI in The Evaluation of The Treated Head and Neck Squamous Cell Carcinoma

Details

Type

Article

Created At

22 Jan 2023