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Background: Despite the advance in treatment modalities of wide range inflammatory skin diseases, tripartite motif- containing (TRIM) proteins are expected to become a potential therapeutic target for prevention and treatment of dermatological disorders.
Objective: Studying the role of TRIM proteins in inflammatory skin diseases.
Material and Methods: We searched the PubMed and Google scholar databases for relevant studies that evaluated the expression of TRIM proteins in inflammatory skin diseases.
Study Selection: All the studies were independently assessed for inclusion. They were included if they fulfilled the following criteria: published in English language, published in peer-reviewed journals, focused on the role of TRIM proteins in inflammatory skin diseases. The initial search presented 30 articles of which 8 met the inclusion criteria. The articles studied the effect of role of TRIM proteins in inflammatory skin diseases.
Data Synthesis: Comparisons were made by structured review with the results tabulated.
Conclusion: We concluded that TRIM proteins play an important role in inflammatory skin diseases development, prognosis and treatment.
DOI
10.21608/ejhm.2020.133965
Keywords
Tripartite motif proteins, TRIM proteins, Inflammatory Skin diseases, Psoriasis, atopic dermatitis
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https://ejhm.journals.ekb.eg/article_133965.html
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https://ejhm.journals.ekb.eg/service?article_code=133965
Publication Title
The Egyptian Journal of Hospital Medicine
Publication Link
https://ejhm.journals.ekb.eg/
MainTitle
Role of TRIM Proteins in Inflammatory Skin Diseases