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133954

Magnesium Sulfate Versus Lidocaine for Attenuating Hemodynamic Response to Tracheal Intubation

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Last updated: 30 Jan 2023

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Abstract

Background: It is well recognized that the occurrence of hemodynamic responses in the form of rise in heart rate and blood pressure during and after laryngoscopy and endotracheal intubation mediated by sympathetic response, is a well- known treat. Objective: The aim of the study was to evaluate effects of magnesium sulfate and lidocaine in attenuating hemodynamic response at a certain doses based on previous studies.
Patients and Methods: 76 patients were randomly divided into two groups (group M and group L) using computer generated randomization table, and induced by magnesium sulphate (30 mg・kg−1) or 2% lidocaine (2 mg・kg−1), infused in 3 minutes using syringe pump, after 3 minutes of pre-oxygenation, we proceeded for anesthetic induction by 2 mg/kg propofol and after loss of consciousness, 0.5 mg/kg atracurium (a muscle relaxant). All patients in both groups were intubated by the same anesthetist (the researcher) with direct laryngoscopy 3 minutes after administration of magnesium sulfate or lidocaine.
Results: There was statistically non-significant difference between the studied groups regarding age, gender, weight, height, body mass index, ASA, presence of diabetes or hypertension, systolic or diastolic blood pressure values baseline, mean arterial blood pressure and heart rate values baseline at a time range of 1 to 5 minutes, while, there was statistically significant difference between the studied groups regarding the same measurements at a time range of 5 to 15 minutes.
Conclusion: we conclude that magnesium sulphate is better alternative to lignocaine for attenuation of stress responses of laryngoscopy and intubation

DOI

10.21608/ejhm.2020.133954

Keywords

Hemodynamic response, Lidocaine, magnesium sulfate

Authors

First Name

Zeinab Hamed

Last Name

Sawan

MiddleName

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Affiliation

Department of Anesthesia and Surgical Intensive care, Faculty of Medicine-Zagazig University.

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Orcid

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First Name

Kamelia Ahmed

Last Name

Abaza

MiddleName

-

Affiliation

Department of Anesthesia and Surgical Intensive care, Faculty of Medicine-Zagazig University.

Email

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City

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Orcid

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First Name

Ahmad

Last Name

Zyada

MiddleName

-

Affiliation

Department of Anesthesia and Surgical Intensive care, Faculty of Medicine-Zagazig University.

Email

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City

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Orcid

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First Name

Ahmad

Last Name

Ezz El Din

MiddleName

-

Affiliation

Department of Anesthesia and Surgical Intensive care, Faculty of Medicine-Zagazig University.

Email

ahmedezz188@gmail.com

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Orcid

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Volume

81

Article Issue

7

Related Issue

19561

Issue Date

2020-10-01

Receive Date

2020-12-30

Publish Date

2020-10-01

Page Start

2,433

Page End

2,438

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 81_Issue 7_Pages 2433-2438.pdf

PDF . 388.1kB

Link

https://ejhm.journals.ekb.eg/article_133954.html

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https://ejhm.journals.ekb.eg/service?article_code=133954

Order

23

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

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Article

Created At

22 Jan 2023