Beta
ManageSearchChatDiscover
132883

Determinants of Anticoagulation Control in Patients Receiving Warfarin Therapy

Article

Last updated: 03 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

-

Abstract

Background: Warfarin, nowadays is considered one of the most prescribed anticoagulant medications. In England for example, there is at least 1% of the whole population being prescribed warfarin. Despite the emergence of new agents of anticoagulants like NOACS, warfarin still prevail in most prescriptions knowing that it can't be substituted in certain indications. Objectives: To assess different factors associated with International Normalized Ratio (INR) control in patients who are on warfarin therapy for different indications. Methods: A retrospective cohort study conducted in National Heart Institute Outpatient Anticoagulation Clinic over six-month period. It included 250 patients on warfarin therapy for different indications. Results: After calculating Time in Therapeutic Range (TTR) of each patient the level of anticoagulation control was determined using the following cut off values: a) Good control: TTR>70%, b) Intermediate control: TTR 50 -70 %, c) Poor control: TTR <50%. Majority of patients in our study 62% had poor control with TTR less than 50%. Conclusion: Majority of patients have poor anticoagulation control by means of TTR. Male gender, higher education and employment status are associated with higher mean TTR and better anticoagulation control. Male gender and employment were significant predictors for good INR control.

DOI

10.21608/ejhm.2020.132883

Keywords

anticoagulation, INR control, Warfarin

Authors

First Name

Mohammad Hossam Eldeen

Last Name

Al-Shaer

MiddleName

-

Affiliation

Cardiovascular Medicine Department, Faculty of Medicine, Zagazig University.

Email

-

City

-

Orcid

-

First Name

Mohammad Gouda

Last Name

Mohammad

MiddleName

-

Affiliation

Cardiovascular Medicine Department, Faculty of Medicine, Zagazig University.

Email

-

City

-

Orcid

-

First Name

Islam Galal Sayed

Last Name

Ahmed

MiddleName

-

Affiliation

Cardiovascular Medicine Department, Faculty of Medicine, Zagazig University.

Email

-

City

-

Orcid

-

First Name

Ahmed Mohammed Badawy

Last Name

Ibrahim

MiddleName

-

Affiliation

Cardiovascular Medicine Department, Faculty of Medicine, Zagazig University.

Email

ahmedbadawy.md89@gmail.com

City

-

Orcid

-

Volume

81

Article Issue

7

Related Issue

19561

Issue Date

2020-10-01

Receive Date

2020-12-27

Publish Date

2020-10-01

Page Start

2,389

Page End

2,394

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 81_Issue 7_Pages 2389-2394.pdf

PDF . 561.4kB

Link

https://ejhm.journals.ekb.eg/article_132883.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=132883

Order

15

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Determinants of Anticoagulation Control in Patients Receiving Warfarin Therapy

Details

Type

Article

Created At

22 Jan 2023