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132881

Pregnancy Rate in Frozen Cycles Transfer After Freeze-All Policy to Prevent Ovarian Hyper Stimulation Syndrome

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Last updated: 24 Dec 2024

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Abstract

Background: Ovarian hyperstimulation syndrome (OHSS) is an iatrogenic state, potentially lethal, and still one of the major complications encountered during controlled ovarian stimulation (COS) in IVF. It occurs in approximately 1ā€“14 % of assisted reproductive technique (ART) cycles and is related to increased vascular permeability. There are two forms of (OHSS) early and late form.
Objectives: The aim of the study was to evaluate the pregnancy rate from frozen thawed embryo transfer after freeze-all policy for patient with high risk for OHSS.
Patients and methods: This is cohort study conducted at Genetics and Infertility Unit, Department of Obstetrics and Gynecology, Zagazig University and a private center (retro- prospective and record-based data). The study was carried out on 150 infertile cases. They were divided into three groups. Group A: Frozen thawed embryo transfer after freeze-all policy for cases of high risk to OHSS, group B: frozen thawed embryo transfer for cases with normal ovarian response and group C: Fresh embryo transfer in cycles with 6 or more oocytes with antagonist protocol.
Results: The main results of the study revealed that there was high statistically significant difference between groups regarding pregnancy outcomes. Pregnancy rate in frozen cycles is better than fresh cycles in normal responders with no late OHSS and less severe early OHSS. Conclusion: Freeze-all policy improves pregnancy rate in high and normal responders. Also, it prevents late OHSS.

DOI

10.21608/ejhm.2020.132881

Keywords

Frozen Embryo Transfer, cryopreservation, OHSS, art

Authors

First Name

Mohammed Abdel-hakim Ahmed

Last Name

Mohammed

MiddleName

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Affiliation

Department of Obstetrics and Gynecology, Faculty of Medicine, Zagazig University, Egypt.

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First Name

Ahmed Ahmed Mohammed

Last Name

Amer

MiddleName

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Affiliation

Department of Obstetrics and Gynecology, Faculty of Medicine, Zagazig University, Egypt.

Email

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Orcid

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First Name

Eman Mahfouz

Last Name

Hafez

MiddleName

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Affiliation

Department of Obstetrics and Gynecology, Faculty of Medicine, Zagazig University, Egypt.

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City

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Orcid

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First Name

Walid Mohamed Sayed Ahmed Zidan

Last Name

El-Nagar

MiddleName

-

Affiliation

Department of Obstetrics and Gynecology, Faculty of Medicine, Zagazig University, Egypt.

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Volume

81

Article Issue

7

Related Issue

19561

Issue Date

2020-10-01

Receive Date

2020-12-27

Publish Date

2020-10-01

Page Start

2,374

Page End

2,378

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 81_Issue 7_Pages 2374-2378.pdf

PDF . 405.6kB

Link

https://ejhm.journals.ekb.eg/article_132881.html

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https://ejhm.journals.ekb.eg/service?article_code=132881

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Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Pregnancy Rate in Frozen Cycles Transfer After Freeze-All Policy to Prevent Ovarian Hyper Stimulation Syndrome

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Article

Created At

22 Jan 2023