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Background: Parkinson's disease (PD) is the most common movement disorder and represents the second most common degenerative disease of the central nervous system.
Objective: To measure the effect of repetitive transcranial magnetic stimulation (rTMS) as therapeutic treatment on sleep disorders in patients with Parkinson's disease (PD).
Patients and methods: This double-blinded study included 20 PD patients (10 received real rTMs and 10 received sham rTMs) patients recruited from Inpatient and Outpatient Clinic of Neuropsychiatric Department of Aswan University Hospital. Our patients were divided into 2 groups (10 patients each). Results: As regards the effect of rTMs on PDSS and sleep latency, our study results found no significant change in Parkinson disease sleep scale between both groups but there was significant change in sleep latency that it decreased in the group received real rTMS in comparison with the SHAM group. In addition, there were significant changes in wake stage and rapid eye movement stage that both decreased in response to rTMS while there was no significant changes in non-rapid eye movement stage. Awakening after being asleep on both studied groups showing significant decrease in wake after sleep onset and wake after persistent sleep as both of them decrease wit rTMS. Conclusion: The main finding of this study was that 10 sessions of 20–Hz rTMS applied over both parietal area improved the subjective as well as the objective sleep quality as reflected by a decrease of frequency in arousal from sleep and in Non-REM–1 stage sleep.
DOI
10.21608/ejhm.2020.127955
Keywords
Parkinson’s disease, Transcranial magnetic stimulation, sleep disorders
Authors
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Abeer Abd El Hady
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ranasholok2020.rg@gmail.com
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https://ejhm.journals.ekb.eg/article_127955.html
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https://ejhm.journals.ekb.eg/service?article_code=127955
Publication Title
The Egyptian Journal of Hospital Medicine
Publication Link
https://ejhm.journals.ekb.eg/
MainTitle
The role of Therapeutic Repetitive Transcranial Magnetic Stimulation in Treatment of Sleep Disorders in Parkinson’s disease Patients