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124872

Changes in Fetal and Uteroplacental Doppler Waveforms After Antenatal Dexamethasone Administration in Women at Risk of Spontaneous Preterm Birth

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Last updated: 03 Jan 2025

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Abstract

Background: Early detection of fetal risk is one of the main issues in today's obstetrics. Ultrasound diagnosis plays a significant role, as the introduction of the Doppler imaging method in the evaluation of blood flow has enabled non- invasive assessment of uteroplacental circulation.
Objective: To assess the impact of maternal dexamethasone on doppler waveforms velocity flow of the fetal umbilical and middle cerebral arteries and maternal uterine arteries in pregnant women at risk of preterm labor with normal fetal vascular resistance. Patients and methods: This cross-sectional study was conducted at the Department of Obstetrics and Gynecology at Menoufia University hospital on 36 patients who were diagnosed as having threatened preterm birth. All the patients were enrolled in the study with routine follow up according to local protocols in the period between January 2019 and November 2019. Full history taking, full general, obstetric examination, and Ultrasound examination was performed. Results: After dexamethasone administration, Umbilical A resistive and Pulsatility indexes were significantly decreased to (1.084 ± 0.118 and 0.66 ± 0.054) in comparison to before dexamethasone (1.121±0.124 and 0.70±0.058). Regarding the Uterine Doppler values, mean Pulsatility index before dexamethasone was 0.79±0.049 (right) and 0.78 ±0.038 (left) decreased significantly to 0.78±0.044 (right) and 0.77±0.036 (left) after dexamethasone. Similarly, the mean Resistive index before dexamethasone was 0.55±0.027 (right) and 0.54±0.026 (left) decreased significantly to 0.53±0.023 (for right and left) after dexamethasone. Conclusions: dexamethasone administration for the pregnant mothers at risk of preterm labor enhance the flow of blood to the fetal umbilical, middle cerebral arteries and maternal uterine arteries 24 hrs. after its administration.

DOI

10.21608/ejhm.2020.124872

Keywords

antenatal, dexamethasone, Doppler waveforms, Fetal Health, preterm birth, Uteroplacental

Authors

First Name

Mohamed Elsibai

Last Name

Anter

MiddleName

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Affiliation

Obstetrics and Gynecology Department, Faculty of Medicine, Menoufia University, Menoufia, Egypt

Email

mohamedsibai681@yahoo.com

City

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Orcid

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First Name

Ayman Abd Elkader

Last Name

Shabana

MiddleName

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Affiliation

Obstetrics and Gynecology Department, Faculty of Medicine, Menoufia University, Menoufia, Egypt

Email

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City

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Orcid

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First Name

Sally Mohamed Ali

Last Name

Badr

MiddleName

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Affiliation

Obstetrics and gynecology department, El-Bagour general Hospital, Menoufia, Egypt

Email

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City

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Orcid

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First Name

Nehad Mahmoud

Last Name

Hoseny

MiddleName

-

Affiliation

Obstetrics and Gynecology Department, Faculty of Medicine, Menoufia University, Menoufia, Egypt

Email

-

City

-

Orcid

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Volume

81

Article Issue

5

Related Issue

18366

Issue Date

2020-10-01

Receive Date

2020-11-22

Publish Date

2020-10-01

Page Start

2,046

Page End

2,053

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 81_Issue 5_Pages 2046-2053.pdf

PDF . 592.3kB

Link

https://ejhm.journals.ekb.eg/article_124872.html

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https://ejhm.journals.ekb.eg/service?article_code=124872

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20

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Changes in Fetal and Uteroplacental Doppler Waveforms After Antenatal Dexamethasone Administration in Women at Risk of Spontaneous Preterm Birth

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Type

Article

Created At

22 Jan 2023