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124800

Vitamin D Levels in Full-Term Neonates with Indirect Hyperbilirubinemia

Article

Last updated: 24 Dec 2024

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Abstract

Background: Jaundice is a common clinical sign in neonatal medicine. Considering the different roles of vitamin D, its lower level may be correlated with neonatal jaundice. Objectives: This study aimed to demonstrate the relationship between serum vitamin D level and neonatal hyperbilirubinemia and to measure its level in their mothers. Subjects and methods: This case-control study was conducted on 90 neonates and their mothers, 60 neonates with hyperbilirubinemia in patients group and 30 healthy neonates age and sex matched in control group < /span>. Blood samples from neonates and their mothers were obtained and sent for laboratory estimation of 25-hydroxy vitamin D, calcium, magnesium, phosphorus, alkaline phosphatase and parathyroid hormone. Results: There is highly significant decrease of vitamin D levels among patients than controls, significant negative correlation between vitamin D levels and serum bilirubin in neonates and no significant difference regarding different laboratory parameters among their mothers. Conclusion: Decreased levels of vitamin D were significantly correlated with neonatal indirect hyperbilirubinemia so, low vitamin D can be included among risk factors for neonatal jaundice.

DOI

10.21608/ejhm.2020.124800

Keywords

Jaundice, Mothers, Neonatal, Vitamin D

Authors

First Name

Neveen T.

Last Name

Abed

MiddleName

-

Affiliation

Department of Pediatrics, Faculty of Medicine, Benha University, Egypt

Email

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City

-

Orcid

-

First Name

Farida F.

Last Name

Negm

MiddleName

-

Affiliation

Department of Pediatrics, Faculty of Medicine, Benha University, Egypt

Email

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City

-

Orcid

-

First Name

Enas S.

Last Name

Ahmad

MiddleName

-

Affiliation

Department of Clinical and Chemical Pathology, Faculty of Medicine, Benha University, Egypt

Email

-

City

-

Orcid

-

First Name

Heba A.

Last Name

Mohammed

MiddleName

-

Affiliation

Department of Pediatrics, Faculty of Medicine, Benha University, Egypt

Email

heba.anwar.soliman@gmail.com

City

-

Orcid

-

Volume

81

Article Issue

5

Related Issue

18366

Issue Date

2020-10-01

Receive Date

2020-11-22

Publish Date

2020-10-01

Page Start

2,030

Page End

2,035

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 81_Issue 5_Pages 2030-2035.pdf

PDF . 454.3kB

Link

https://ejhm.journals.ekb.eg/article_124800.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=124800

Order

18

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Vitamin D Levels in Full-Term Neonates with Indirect Hyperbilirubinemia

Details

Type

Article

Created At

22 Jan 2023