124774

Clinical Outcomes of Upper Gastrointestinal Bleeding in Egyptian Patients with Decompensated Liver Cirrhosis, Does the Bleeding Source Matter?

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Last updated: 03 Jan 2025

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Abstract

Background: Upper gastrointestinal bleeding (UGIB) is a prevalent emergency and mortality cause in cirrhotic patients. It prolongs the hospital length of stay (LOS) and increases hospital readmission. Objectives: We investigated the clinical outcomes of acute variceal bleeding (AVB) and non-variceal bleeding (NVB) in patients with decompensated cirrhosis and the possible risk factors for prolonged hospital LOS. Patients and Methods: All patients with decompensated liver cirrhosis and UGIB (AVB & NVB) hospitalized from August 2018 to March 2019 were enrolled in this study. We assessed mortality rate, the hospital LOS and hospital readmission rate along with the probable risk factors associated with prolonged hospital LOS. Results: Our study included 582 patients with decompensated liver cirrhosis, 367 patients had AVB and 215 patients had NVB. There was no significant difference in mortality rate between both groups (11.4% vs. 9.3%, P= 0.43). The hospital LOS in AVB patients was longer than that in NVB group (5.8 ± 2.2 vs. 4.3 ± 1.8, p=0.001). Rate of hospital re-admission within 30 days was significantly higher in the AVB group (27%) compared to NVB group (18%). Inhospital re-bleeding and the need for repeated endoscopy were also higher in AVB patients (20%) than in NVB patients (12%). Risk factors for prolonged hospital LOS were development of hepatic encephalopathy, spontaneous bacterial peritonitis (SBP), in-hospital re-bleeding, Child C score and higher Model for end-stage liver disease (MELD) score. Conclusion: Patients with decompensated cirrhosis and AVB have longer hospital LOS and re-hospitalization rate than those with NVB with no significant difference in mortality rate between both groups.

DOI

10.21608/ejhm.2020.124774

Keywords

Decompensated cirrhosis, variceal bleeding, Non-variceal bleeding, Peptic ulcer, length of hospital stay, In-hospital re-bleeding

Authors

First Name

Mohamed S

Last Name

Mohamed

MiddleName

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Affiliation

Internal Medicine Department, Faculty of Medicine, Zagazig University

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City

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Orcid

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First Name

Mohamed G

Last Name

Hamed

MiddleName

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Affiliation

Internal Medicine Department, Faculty of Medicine, Zagazig University

Email

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City

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Orcid

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First Name

Amr S

Last Name

Hanafy

MiddleName

-

Affiliation

Internal Medicine Department, Faculty of Medicine, Zagazig University

Email

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City

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Orcid

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First Name

Mohamed AA

Last Name

Bassiony

MiddleName

-

Affiliation

Internal Medicine Department, Faculty of Medicine, Zagazig University

Email

dr_mbh13303@yahoo.com

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Volume

81

Article Issue

5

Related Issue

18366

Issue Date

2020-10-01

Receive Date

2020-11-22

Publish Date

2020-10-01

Page Start

2,001

Page End

2,005

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_124774.html

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https://ejhm.journals.ekb.eg/service?article_code=124774

Order

13

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Clinical Outcomes of Upper Gastrointestinal Bleeding in Egyptian Patients with Decompensated Liver Cirrhosis, Does the Bleeding Source Matter?

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Article

Created At

22 Jan 2023