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121013

Comparative Study between Simple Percutaneous Transluminal Angioplasty and Drug-Coated Balloons in Chronic Total Occlusion of The Femoro-popliteal Artery

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Last updated: 03 Jan 2025

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Abstract

Background: Atherosclerotic peripheral artery disease (PAD) affects a growing number of patients in aging populations. Peripheral artery disease (PAD) accounts for a large proportion of cardiovascular disease (CVD) prevalence in most world regions.
Objective: This study aims to evaluate and compare the patency, clinical outcome, and limb salvage rates between the simple percutaneous Transluminal angioplasty and the drug-coated balloons in chronic total occlusion of the femoropopliteal arterial segment on the short-term course.
Patients and Method: A prospective randomized controlled comparative study was conducted in the vascular surgery department; Aswan University Hospital during the period from March 2018 to March 2020. In total, 30 patients with a well-established diagnosis of superficial femoral artery (SFA) and/or proximal popliteal lesions with symptoms of PAD.
Results: The primary patency at 12-month following treatment with DCB was significantly better 100. %, 80.0%, 60.0% at 1, 6, 12 months compared with POBA 86.7 %, 66.7%, 46.7% at 1, 6, 12 months. The rate of clinically- driven TLR was the same in both groups (26.6%). The use of DCB was safe and did not increase the major adverse clinical events (death, myocardial infarction, and minor or major amputation) when compared with those seen with the use of the uncoated balloons).
Conclusion: Use of DCBs is associated with improved vessel patency when compared to POBA in patients with FPD. There was no difference in clinically driven TLR between DCB and POBA in our study.

DOI

10.21608/ejhm.2020.121013

Keywords

DCB, Patency, limb salvage, TLR, POBA

Authors

First Name

Emad El-dien Ahmed

Last Name

Hussein

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Orcid

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First Name

Mohammed Ahmed Mohammed

Last Name

Ismail

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Email

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Orcid

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First Name

Ali Mahmoud Mohammed

Last Name

Galal

MiddleName

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Affiliation

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Email

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Orcid

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First Name

Ahmed Khalf

Last Name

Fathy

MiddleName

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Orcid

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Volume

81

Article Issue

4

Related Issue

18005

Issue Date

2020-10-01

Receive Date

2020-11-01

Publish Date

2020-10-01

Page Start

1,866

Page End

1,871

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 81_Issue 4_Pages 1866-1871.pdf

PDF . 250.7kB

Link

https://ejhm.journals.ekb.eg/article_121013.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=121013

Order

23

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Comparative Study between Simple Percutaneous Transluminal Angioplasty and Drug-Coated Balloons in Chronic Total Occlusion of The Femoro-popliteal Artery

Details

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Article

Created At

22 Jan 2023