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120449

Comparative Study between Treatment by Vacuum-Assisted Closure (VAC), Treatment by Hyperbaric Oxygen Therapy and Traditional Treatment of Diabetic Foot Infection

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Last updated: 03 Jan 2025

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Abstract

Aim: To compare the therapeutic effects of vacuum-assisted closure therapy, hyperbaric oxygen therapy, and traditional moist dressings in improving the healing process of chronic diabetic foot infection.
Study design: A prospective randomized study.
Patients and Methods: A total of 75 patients, with a chronic diabetic foot infection, were included in this study. After surgical debridement, all patients were randomly classified into 3 groups, with 25 patients in each group. Group A were treated by VAC therapy, Group B were treated by HBOT and Group C were treated by traditional moist dressings respectively. Wounds were evaluated every week for six weeks as regards the size, timing of healthy granulation tissue formation, local wound complications, and number of debridement sessions.
Results: There was a significant reduction in the wound size in group A with a mean of 70.25 %, B with 62.65 % compared to group C with 32.46 %. As regards healthy granulation tissue formation onset, it was more rapid in group A with a mean of 6.5, B with 7 compared to group C with 14 days. As regards the number of debridement sessions and local wound complications they were significantly less in group A than the other two groups.
Conclusion: Vacuum-assisted closure (VAC) therapy appears to be safe, more effective with less complications than the other two methods in the treatment of diabetic foot infection, and can be used with HBOT simultaneously if indicated.

DOI

10.21608/ejhm.2020.120449

Keywords

Vacuum-assisted closure, VAC, hyperbaric oxygen therapy, traditional moist dressings, chronic diabetic foot infection

Authors

First Name

Ahmed El-Said

Last Name

Mousa

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Affiliation

Department of General Surgery, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.

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First Name

Mahmoud Salah

Last Name

Shehata

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Affiliation

Department of General Surgery, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.

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Orcid

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First Name

Mohamed Mohsen

Last Name

Salem

MiddleName

-

Affiliation

Department of General Surgery, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.

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Volume

81

Article Issue

4

Related Issue

18005

Issue Date

2020-10-01

Receive Date

2020-10-26

Publish Date

2020-10-01

Page Start

1,810

Page End

1,814

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 81_Issue 4_Pages 1810-1814.pdf

PDF . 598.4kB

Link

https://ejhm.journals.ekb.eg/article_120449.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=120449

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15

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Comparative Study between Treatment by Vacuum-Assisted Closure (VAC), Treatment by Hyperbaric Oxygen Therapy and Traditional Treatment of Diabetic Foot Infection

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Article

Created At

22 Jan 2023