Beta
ManageSearchChatDiscover
118575

Assessment of Precipitating Factors and Outcomes of Hepatic Encephalopathy in Cirrhotic Patients

Article

Last updated: 30 Jan 2023

OverviewSimilar Items

Subjects

-

Tags

-

Abstract

Background: Hepatic encephalopathy (HE) is one of the major complications of liver cirrhosis (LC). It's defined as a reversible neuropsychiatric event of liver cirrhosis. Up to fifty percent of cirrhotic patients will suffer from at least one attack of HE. Studies examining the prognostic significance of HE are limited despite the high prevalence in cirrhosis. The current study aimed to assess outcome of hepatic encephalopathy.
Patients and methods: Over one year duration, 100 patients with HE were enrolled. All patients were subjected to full history taking and full examination. Patient with central nervous system lesion, metabolic disorders or post-ictal state was excluded. Abdominal ultrasound and ascitic fluid examination were performed in all patients. Patients were followed and their outcome was recorded.
Results: Mean age of patients was 53.19 ±3.6 years and the majority of patients were males. Hepatitis C infection was the most frequent cause of LC. The main precipitating factor for HE was infection (29%) followed by hematemesis (24%) and constipation (19%). In 19 (19%) patients, there was evidence of ascitic fluid infection. Out of studied patients; 81 (81%) patients were alive. It was noticed that hematemesis and infection were significantly higher in dead patients. Conclusion: hepatic encephalopathy is a serious event in patients with LC. Major precipitating factors were infection, hematemesis and constipation. Infection and hematemesis are usually associated with poor outcome. 

DOI

10.21608/ejhm.2020.118575

Keywords

hepatic encephalopathy, Hepatitis C infection, Liver cirrhosis

Authors

First Name

Mohamed Zain Eldeen

Last Name

Hafez

MiddleName

-

Affiliation

Department of Internal Medicine, Faculty of Medicine, Assiut University, Assiut, Egypt

Email

-

City

-

Orcid

-

First Name

Hala Abdallah Mahmoud

Last Name

Abdallah

MiddleName

-

Affiliation

Department of Internal Medicine, Faculty of Medicine, Aswan University, Aswan, Egypt

Email

-

City

-

Orcid

-

First Name

Mohamed Anwar Mohamed

Last Name

Hamad

MiddleName

-

Affiliation

Department of Internal Medicine, Faculty of Medicine, Aswan University, Aswan, Egypt

Email

-

City

-

Orcid

-

Volume

81

Article Issue

3

Related Issue

17515

Issue Date

2020-10-01

Receive Date

2020-10-13

Publish Date

2020-10-01

Page Start

1,718

Page End

1,721

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 81_Issue 3_Pages 1718-1721.pdf

PDF . 680.6kB

Link

https://ejhm.journals.ekb.eg/article_118575.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=118575

Order

30

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

-

Details

Type

Article

Created At

22 Jan 2023