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118573

Combined Topo-Guided laser Vision Correction (LASIK) with Concurrent Prophylactic High-Fluence Corneal Collagen Crosslinking (CXL) in Myopic Patients with Normal Cornea

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Last updated: 03 Jan 2025

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Abstract

Background: Corneal ectasia is a serious vision-threatening complication of laser-assisted in-situ keratomileusis (LASIK). Objective: The aim of the work was to evaluate the efficacy and safety of ultraviolet A (UVA) irradiation crosslinking in concurrent with LASIK in myopic patient with normal cornea to avoid post LASIK ectasia.
Patients and Methods: This Prospective randomized interventional study included 60 eyes of 30 consecutive patient who were scheduled for LASIK surgery, all of them were myopic with normal cornea with no pervious refractive surgery. They were candidate for Combined Topo-Guided LASIK with accelerated CXL. This was done in a private eye hospital between Jun 2018 and Jun 2019. Results: The preoperative uncorrected visual acuity (UCVA) ranged from 0.05- 0.1 with mean 0.075±0.02 and preoperative best corrected visual acuity (BCVA) ranged 0.2- 1.0 with mean 0.58±0.13 and post-operative UCVA at 6 months showed ranged 0.2-1.0 with mean 0.55±0.16, and postoperative UCVA at 1 year showed ranged 0.2-1.0 with mean 0.56±0.13,. The improvement in visual acuity from 0.075±0.02 UCVA preoperatively show statistically significant difference (P > 0.05) because we compared the results with the preoperative BCVA 0.58±0.13 postoperatively at 6 months. However, t-Paired Sample t-test; p-value < 0.05 S. Conclusion: It could be concluded that LASIK combined with a prophylactic CXL intervention appears to provide predictability as well as refractive and keratometric stability. The data reported in this study provide evidence of the safety and efficacy of this approach.

DOI

10.21608/ejhm.2020.118573

Keywords

LASIK, CXL, Myopic Patients, Normal Cornea

Authors

First Name

Khaled EL-Ghonemy Said

Last Name

Ahmed

MiddleName

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Affiliation

Department of Ophthalmology, Faculty of Medicine, Menoufia University, Egypt

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Orcid

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First Name

Hany Ahmed

Last Name

Khiry

MiddleName

-

Affiliation

Department of Ophthalmology, Faculty of Medicine, Menoufia University, Egypt

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Orcid

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First Name

Ahmed Ibrahim

Last Name

Basiony

MiddleName

-

Affiliation

Department of Ophthalmology, Faculty of Medicine, Menoufia University, Egypt

Email

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City

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Orcid

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First Name

Rana Mohamed Amer

Last Name

Elwakiel

MiddleName

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Affiliation

Department of Ophthalmology, Faculty of Medicine, Menoufia University, Egypt

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City

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Orcid

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Volume

81

Article Issue

3

Related Issue

17515

Issue Date

2020-10-01

Receive Date

2020-10-13

Publish Date

2020-10-01

Page Start

1,704

Page End

1,709

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 81_Issue 3_Pages 1704-1709.pdf

PDF . 480.3kB

Link

https://ejhm.journals.ekb.eg/article_118573.html

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https://ejhm.journals.ekb.eg/service?article_code=118573

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Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Combined Topo-Guided laser Vision Correction (LASIK) with Concurrent Prophylactic High-Fluence Corneal Collagen Crosslinking (CXL) in Myopic Patients with Normal Cornea

Details

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Article

Created At

22 Jan 2023