117023

Influence of Overweight and Obesity on Bone Mineral Density in Egyptian Premenopausal Women

Article

Last updated: 03 Jan 2025

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Abstract

Background and objective: Can overweight and obesity exert a detrimental or a protective effect on bone density in premenopausal women? We studied the correlation between obesity and bone mineral density (BMD) in premenopausal women in Egypt. Patients and methods: a Case-control study included 50 overweight and obese premenopausal women compared to 50 normal weight women of matched age. Clinical history, examination, laboratory tests and DEXA scan were done. Results: T–score and Z-score at the forearm, hip, and lumbar vertebrae were significantly lower in the case group than the control group. In all participants, we found a significant negative correlation between body mass index (BMI) with Z-score ( forearm), BMI and bodyweight with Z-score (hip) and BMI, waist circumference (WC) and bodyweight with Z-score (lumbar vertebrae). We found a significant negative correlation between waist/ hip ratio (WHR) and T-score (hip) and between BMI, waist/hip ratio and bodyweight with T-score (lumbar vertebrae). In the overweight and obese participants, BMI was inversely correlated with Z-score (forearm, hip, and lumbar vertebrae) as well as waist circumference with Z-score (lumbar vertebrae). With post-hoc analysis, T-score at the lumbar vertebrae was significantly lower in the obese group. With adjustment of the age, (age and WC) and (age and WHR), we found a significant negative association in the obese group versus the lean group with Z-score (forearm, hip and lumbar vertebrae).
Conclusion: Overweight and obese Egyptian premenopausal women were more vulnerable to lower bone density.

DOI

10.21608/ejhm.2020.117023

Keywords

Bone Mineral Density, Obesity, Premenopausal women

Authors

First Name

Mohammed Ali

Last Name

Gameil

MiddleName

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Affiliation

Internal medicine department, Faculty of medicine, Mansoura University, Mansoura, Dakahlia, Egypt.

Email

drmaligameil1979@yahoo.com

City

mansoura

Orcid

0000-0002-9342-6451

First Name

Ahmed Hassan

Last Name

Elsebaie

MiddleName

-

Affiliation

-

Email

-

City

-

Orcid

-

First Name

Rehab Elsayed

Last Name

Marzouk

MiddleName

-

Affiliation

-

Email

-

City

-

Orcid

-

First Name

Nesma Alaa

Last Name

Elmenebawy

MiddleName

-

Affiliation

-

Email

-

City

-

Orcid

-

Volume

81

Article Issue

3

Related Issue

17515

Issue Date

2020-10-01

Receive Date

2020-10-04

Publish Date

2020-10-01

Page Start

1,654

Page End

1,658

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_117023.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=117023

Order

20

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Influence of Overweight and Obesity on Bone Mineral Density in Egyptian Premenopausal Women

Details

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Article

Created At

22 Jan 2023