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117022

Occult Hepatitis B Virus Infection Among Hemodialysis Patients in Fakous General Hospital

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Last updated: 03 Jan 2025

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Abstract

Background: Occult HBV infection (OBI) is defined as the presence of a small amount of HBV in patients with negative serum for hepatitis B surface antigen (HBs Ag). The serum HBV DNA level in these patients is generally lower than 104 copies/mL, there is a high prevalence of OBI in patients with chronic hepatitis C, HCC cryptogenic liver disease, and HIV. Objectives: Assessment of prevalence of Occult Hepatitis B Virus infection among hemodialysis patients in Fakous General Hospital. Patients and Methods: A total of 40 patients with end-stage renal disease undergoing regular HD (for at least 6 months underwent a complete physical examination. Serum samples were collected between before hemodialysis and then stored at -80C° until tested. Serological markers of HBV infection (HBsAg, anti-HBs, anti-HBc) were determined using standard third generation commercially available enzyme immunoassays).
Results: The 40 patients who have been included in this study had a minimum age of 25 years and a maximum age of 78 years. The number of females was 25 with a percentage of 62.5% and the percentage of males was about 37.5% (15 males). 22 patients (55%) had negative sera for anti-HCV antibody and a percentage of 37% and 63% for the distribution of females and males, respectively. 18 patients (45%) had positive sera for anti-HCV antibody and 37% of them were females and 63% of them were males. Conclusions: OBI infection is a relatively common infection (37.5%) among chronic hemodialysis patients in the dialysis unit of Fakous general hospital.

DOI

10.21608/ejhm.2020.117022

Keywords

Occult Hepatitis B Virus Infection, Haemodialysis Patients, Fakous General Hospital

Authors

First Name

Asmaa Sobhy

Last Name

Mohamed

MiddleName

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Affiliation

Department of Internal Medicine, Faculty of Medicine, Zagazig University, Sharkia, Egypt

Email

asmaasobhy@gmail.com

City

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Orcid

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First Name

Nermien Raaft

Last Name

abdel Fattah

MiddleName

-

Affiliation

Department of Internal Medicine, Faculty of Medicine, Zagazig University, Sharkia, Egypt

Email

-

City

-

Orcid

-

First Name

Waleed Abdulfattah

Last Name

Ismail

MiddleName

-

Affiliation

Department of Internal Medicine, Faculty of Medicine, Zagazig University, Sharkia, Egypt

Email

-

City

-

Orcid

-

First Name

Emad

Last Name

Abdel-Latif

MiddleName

-

Affiliation

Department of Internal Medicine, Faculty of Medicine, Zagazig University, Sharkia, Egypt

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-

City

-

Orcid

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Volume

81

Article Issue

3

Related Issue

17515

Issue Date

2020-10-01

Receive Date

2020-10-04

Publish Date

2020-10-01

Page Start

1,648

Page End

1,653

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 81_Issue 3_Pages 1648-1653.pdf

PDF . 645.8kB

Link

https://ejhm.journals.ekb.eg/article_117022.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=117022

Order

19

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Occult Hepatitis B Virus Infection Among Hemodialysis Patients in Fakous General Hospital

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Article

Created At

22 Jan 2023