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116787

Candidemia in Preterm Infants in Neonatal Intensive Care Unit at Zagazig University Hospitals

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Last updated: 03 Jan 2025

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Abstract

Background: Candidiasis is a leading cause of blood stream infections in neonatal intensive care units (NICUs) and associated with high mortality and morbidity. Preterm infants are more vulnerable to be affected with candida infections.
Patients and Methods: The study is cross-sectional analytical study aimed to evaluate the magnitude of candidemia and evaluate risk factors, proper management, and clinical outcome of candidemia in preterms in NICU in Zagazig University Hospital. It included (103) preterms, their gestational ages of 30 to 37 weeks with weights of 1 to 3 kg. They were admitted to (NICU) of Pediatric Department and Obstetric and Gynecology Department. Investigations were conducted at the Department of Clinical Pathology and Microbiology at Zagazig University Hospitals during the period of 6 months from November 2018 to April 2019.
Results: 12.6% of the studied group gave positive fungal culture, Candida albicans was the commonest type of fungi found (among 61.5% of the candidemia positive group). 30.8% of candidemia group had taken empirical diflucan as a regimen versus 95.6% of the other group had taken it and the difference between groups was highly statistically significant.
Conclusion: Preterms are more vulnerable to candida infection. Candida albicans is the commonest type and the use of empirical antifungal therapy to preterms at risk reduces the prevalence of candidemia in the NICU.

DOI

10.21608/ejhm.2020.116787

Keywords

Preterm, Candidemia, NICU, Empirical, Antifungals

Authors

First Name

Omima Ahmed Fatooh Abdelhameed

Last Name

Eissa

MiddleName

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Affiliation

Departments of Pediatrics, Faculty of Medicine - Zagazig University

Email

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City

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Orcid

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First Name

Hanaa Abdelfatah

Last Name

Mohammed

MiddleName

-

Affiliation

Departments of Pediatrics, Faculty of Medicine - Zagazig University

Email

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City

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Orcid

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First Name

Tarek Hamed

Last Name

Attya

MiddleName

-

Affiliation

Departments of Pediatrics, Faculty of Medicine - Zagazig University

Email

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City

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Orcid

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First Name

Ghada Elsayed

Last Name

Amr

MiddleName

-

Affiliation

Department of Neonatology and Clinical Pathology, Faculty of Medicine - Zagazig University

Email

-

City

-

Orcid

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Volume

81

Article Issue

3

Related Issue

17515

Issue Date

2020-10-01

Receive Date

2020-10-03

Publish Date

2020-10-01

Page Start

1,603

Page End

1,608

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 81_Issue 3_Pages 1603-1608.pdf

PDF . 444.5kB

Link

https://ejhm.journals.ekb.eg/article_116787.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=116787

Order

11

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Candidemia in Preterm Infants in Neonatal Intensive Care Unit at Zagazig University Hospitals

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Article

Created At

22 Jan 2023