Beta
114450

Subclinical Enthesitis in Rheumatoid Arthritis Patients and its Relation to Disease Parameters and Disease Activity

Article

Last updated: 24 Dec 2024

Subjects

-

Tags

-

Abstract

Background: Rheumatoid Arthritis (RA) is a chronic systemic autoimmune disorder of unknown etiology characterized by symmetrical joint synovitis and pain. RA has a wide clinical spectrum and may vary from mild nonerosive disease to severe inflammation and joint damage with extra articular manifestations. To detect enthesopathy, the European League Against Rheumatism (EULAR) recommends magnetic resonance imaging (MRI) or ultrasonography (US). Objective: To detect subclinical enthesitis in rheumatoid arthritis patients and its relation to disease parameters and disease activity. Patients and Methods: This prospective observational study included 50 adult patients diagnosed as rheumatoid arthritis according to the 2010 ACR-EULAR classification criteria for rheumatoid arthritis. The study was carried out in the Musculoskeletal Ultrasonography Unit of the Rheumatology, Physical Medicine and Rehabilitation Department, Al-Azhar University Hospitals Assiut. Results: We found that the mean age in case group was 46.3 ± 8.4 years. Females accounted for 62% (31 patients) of all patients. The disease duration ranged from one year to 15 years with a mean of 6.2 ± 1.9 years. The BMI was 19.5 ± 42 kg/m2 . Mean of disease activity evaluated by the disease activity score in 28 joints was 4.7 ± 1.5. Our findings demonstrated that prevalence of subclinical enthesitis in patients with rheumatoid arthritis was 32%. There was a statistically significant relation between 28-joint Disease Activity Score (DAS28) score and ultrasound detected enthesitis (p. value < 0.05). Conclusion: BMI, old age and long disease duration were suggested as the risk factors for subclinical enthesitis.

DOI

10.21608/ejhm.2020.114450

Keywords

Subclinical enthesitis, Rheumatoid Arthritis Patients, MRI, US, BMI

Authors

First Name

Mohamed Ismail Mohamed

Last Name

AbdelKareem

MiddleName

-

Affiliation

Department of Rheumatology, Physical Medicine & Rehabilitation, Faculty of Medicine - Al-Azhar University (Assiut)

Email

-

City

-

Orcid

-

First Name

Tarek Mohamed

Last Name

AbdelAziz

MiddleName

-

Affiliation

Department of Rheumatology, Physical Medicine & Rehabilitation, Faculty of Medicine - Al-Azhar University (Assiut)

Email

-

City

-

Orcid

-

First Name

Asmaa Abd ELraheem

Last Name

Borai

MiddleName

-

Affiliation

Department of Rheumatology, Physical Medicine & Rehabilitation, Faculty of Medicine - Al-Azhar University (Assiut)

Email

-

City

-

Orcid

-

Volume

81

Article Issue

2

Related Issue

17338

Issue Date

2020-10-01

Receive Date

2020-09-22

Publish Date

2020-10-01

Page Start

1,438

Page End

1,443

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_114450.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=114450

Order

16

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Subclinical Enthesitis in Rheumatoid Arthritis Patients and its Relation to Disease Parameters and Disease Activity

Details

Type

Article

Created At

22 Jan 2023