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112309

Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis (SREAT): A Case Report

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Last updated: 24 Dec 2024

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Abstract

Background: Steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT), also known as Hashimoto's encephalopathy, is a disorder characterized by an encephalopathy associated with anti-thyroid antibodies in the absence of alternative causes. It has a wide range of clinical, laboratory and radiological features.
Objective: Cases of steroid-responsive encephalopathy associated with autoimmune thyroiditis are difficult to diagnose and requires a high index of suspicion, as this will determine the early timing of management and disease outcome.
Patient and Methods: Here we present a case report of twenty-year-old woman presenting with neurological and psychological symptoms. She was found to have high anti-thyroid peroxidase antibodies (Anti-TPO) with normal thyroid function and negative screening for other etiologies of encephalopathy. Based on her presentation, she was diagnosed with steroid-responsive encephalopathy associated with autoimmune thyroiditis.
Results: Patient was started on high dose steroids upon which she responded partially. Then she required the addition of immunotherapy in the form of Rituximab to improve her symptoms.
Conclusion: After exclusion of other causes of encephalopathy, the presence of thyroid antibodies prompts the susp < /span>icion of SREAT and therefore the early initiation of steroids to improve patients' outcome.

DOI

10.21608/ejhm.2020.112309

Keywords

Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis, SREAT, Hashimoto’s encephalopathy, Encephalopathy, Autoimmune thyroiditis

Authors

First Name

Hessah Abdulaziz

Last Name

Al Hussaini

MiddleName

-

Affiliation

Department of Internal Medicine, College of Medicine, King Faisal University, Al Ahsa, Kingdom of Saudi Arabia

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Orcid

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Volume

81

Article Issue

1

Related Issue

16813

Issue Date

2020-10-01

Receive Date

2020-09-13

Publish Date

2020-10-01

Page Start

1,231

Page End

1,233

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 81_Issue 1_Pages 1231-1233.pdf

PDF . 469.0kB

Link

https://ejhm.journals.ekb.eg/article_112309.html

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https://ejhm.journals.ekb.eg/service?article_code=112309

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12

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Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis (SREAT): A Case Report

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Article

Created At

22 Jan 2023