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110698

Cord Blood Albumin as a Predictor of Neonatal Jaundice

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Last updated: 03 Jan 2025

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Abstract

Background: Neonatal jaundice is a very common condition worldwide occurring in up to 60% of term and 80% of preterm newborns in the first week of life. Even though extreme hyperbilirubinemia is rare in developed countries it is still quite rife in developing countries often resulting in kernicterus with its attendant medical, economic and social burden on the patient, family and society.
Objective: The present study was conducted to evaluate the predictive value of umbilical cord blood albumin level for subsequent neonatal jaundice in healthy full-term neonates.
Patients and Methods: The current study was carried out in the Pediatric Department, Faculty of Medicine, Aswan University Hospital. The study was conducted on 100 healthy full-term newborn after obtaining consent from parents. Cord blood was collected at birth and cord blood albumin estimation was done.
Results: The incidence of neonatal hyperbilirubinemia in our study (64%). In terms of demographic data: males represented (32.5 %) of the jaundiced cases in the study and females represented (62.5 %); the difference was statistically insignificant (P value 0.325). Cord serum albumin level of (> 3.3) g/dl has a sensitivity of (86%) and specificity of (80%), PPV (81%), NPV of (85%) and the accuracy rate was (83 %) in predicting neonatal hyperbilirubinemia.
Conclusion: There is significant correlation between cord serum albumin level and neonatal hyperbilirubinemia in healthy full-term neonates ≥ 2.5 kg birth weight and that serum albumin level taken from the blood of the umbilical cord is an effective way to predict neonatal hyperbilirubinemia in term healthy infants.

DOI

10.21608/ejhm.2020.110698

Keywords

Cord Blood Albumin, Predictor of Neonatal Jaundice, Hyperbilirubinemia

Authors

First Name

Hanan Mohamed Abd El-Moneim

Last Name

Awad

MiddleName

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Affiliation

Department of Pediatrics, Faculty of Medicine - Aswan University

Email

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City

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Orcid

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First Name

Mohamed Nashat Moawed

Last Name

Hasan

MiddleName

-

Affiliation

Department of Pediatrics, Faculty of Medicine - Aswan University

Email

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City

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Orcid

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First Name

Ghadeer Sayed Mostafa

Last Name

Khaleil

MiddleName

-

Affiliation

Department of Pediatrics, Faculty of Medicine - Aswan University

Email

dr.ghadeersayed@yahoo.com

City

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Orcid

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Volume

81

Article Issue

1

Related Issue

16813

Issue Date

2020-10-01

Receive Date

2020-09-03

Publish Date

2020-10-01

Page Start

1,217

Page End

1,225

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 81_Issue 1_Pages 1217-1225.pdf

PDF . 614.8kB

Link

https://ejhm.journals.ekb.eg/article_110698.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=110698

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Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Cord Blood Albumin as a Predictor of Neonatal Jaundice

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Article

Created At

22 Jan 2023