Beta
108892

Comparison between Dexmedetomidine or Magnesium Sulfate as Adjuvants to Bupivacaine for Caudal Anesthesia in Pediatric Patients Undergoing Infraumbilical Surgeries

Article

Last updated: 03 Jan 2025

Subjects

-

Tags

-

Abstract

Background: Caudal epidural anesthesia is a common technique providing intra and postoperative analgesia in pediatric infraumbilical surgical procedures. Objectives: The aim of this study was to compare the effect of adding Dexmedetomidine or Magnesium Sulfate as an adjuvant to Bupivacaine for caudal anesthesia in pediatric infraumbilical surgeries. Patients and Methods: This randomized controlled prospective study was done at Sohag University Hospital on sixty pediatric patients with American Society of Anesthesiologists (ASA) Classes I or II or III, weighted up to 20 kg scheduled for infraumbilical surgeries using caudal block in the period between January 2019 and January 2020. The included subjects were divided into three groups, twenty patients each: Group C (control), Group D (Dexmedetomidine group) and Group M (Magnesium group). Results: In our study, the caudal block mainly used to relieve pain after Sevoflurane anesthesia with less incidence of emergence agitation. On comparing (Group D) and (Group M), Face, Legs, Activity, Cry, Consolability scale (FLACC) score was lower in (Group D: 0,1,1,2) than (Group M: 1,1,2,2) without significant difference at postoperative set times (30 minutes,1,2,3 hours), respectively. At the 6th hour postoperatively, (Group M) patients achieved higher FLACC scores (3) compared with (Group D) patients (2.5) with statistically significant difference with P value of 0.05. During the first 3 hours post-operative, there were higher sedation scores in (Group D: 4,4,3,3) and (Group M: 4,4,3,2.5) more than (Control group: 3,2.5,2,2) with highly statistical significant difference with (P value < 0.001) at (30 minutes,1h, 2h, 3 hours), respectively. At the 6th hour postoperatively, there were higher sedation scores with (Group D) (3) more than (Group M) (2) with highly statistical significant difference with (P value < 0.001). Conclusion: Administration of Dexmedetomidine as adjuvant with Bupivacaine enhances caudal block, prolongs duration of postoperative analgesia, reduces postoperative EA and provides preferred postoperative sedation in pediatric patient undergoing infraumbilical surgeries with minimum adverse effects compared to Magnesium Sulfate as adjuvant.

DOI

10.21608/ejhm.2020.108892

Keywords

Dexmedetomidine, magnesium sulfate, Bupivacaine, Caudal anesthesia, Infraumbilical surgeries, postoperative agitation

Authors

First Name

Ahmed El-Saeed Abd El-Rahman

Last Name

Ali

MiddleName

-

Affiliation

-

Email

-

City

-

Orcid

-

First Name

Wesam Abd El-Galil

Last Name

Abu-Elwafa

MiddleName

-

Affiliation

-

Email

-

City

-

Orcid

-

First Name

Ghada Abdel-Gaber

Last Name

Rezk

MiddleName

-

Affiliation

-

Email

-

City

-

Orcid

-

First Name

Mariam Helal

Last Name

Rasmy

MiddleName

-

Affiliation

-

Email

-

City

-

Orcid

-

Volume

80

Article Issue

3

Related Issue

15828

Issue Date

2020-07-01

Receive Date

2020-08-20

Publish Date

2020-07-01

Page Start

1,126

Page End

1,137

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_108892.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=108892

Order

28

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Comparison between Dexmedetomidine or Magnesium Sulfate as Adjuvants to Bupivacaine for Caudal Anesthesia in Pediatric Patients Undergoing Infraumbilical Surgeries

Details

Type

Article

Created At

22 Jan 2023