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106016

Renal Impairment and Nonalcoholic Fatty Liver Disease. Disease – Disease Relationship

Article

Last updated: 24 Dec 2024

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Abstract

Background: Nonalcoholic fatty liver disease (NAFLD) has emerged as serious growing global health problem worldwide and its association with the progression of renal impairment (RI). Accumulating evidence suggests that NAFLD and RI are sharing the same cardio metabolic risk factors.
Objective: to evaluate and investigate the confounding factors sharing in the relation between NAFLD and renal impairment (RI).
Patients and Methods: 250 Egyptian patients with NAFLD were investigated for creatinine, ALT, AST, lipid profile, fasting blood sugar. Questionnaire and physical examination were done to explore the relationship between NAFLD and RI.
Result: HA1C was 6.0±0.31, cholesterol 210.05±36.67, triglyceride 162.59±35.06, LDL 146.02±16.7 and HDL 43.23±6.15. AST and ALT were 34.12±4.28 and 35.34±4.8 respectively. ALP was 72.49±6.56, Cr 0.99±0.11, urea 29.16±9.41 and e-GFR 89.67±9.95. 39.2% were smokers 39.6% were Hypertensive, 60.8% had dyslipidemia and 27.6% had metabolic syndrome. 22.4% were cardiac patients and asthma represented 17.2% of the studied group. Renal impairment group was significantly associated with higher age and higher HA1C and also with higher Cr and urea but with lower GFR. We found also significant association between RI and males, hypertension, dyslipidemia, metabolic syndrome and asthma, with no other significant relation found. Conclusion: There is strong and close association between factors and precipitating factors.

DOI

10.21608/ejhm.2020.106016

Keywords

renal impairment, Nonalcoholic fatty liver

Authors

First Name

Said Abd Elbaky Gad

Last Name

Shams El Deen

MiddleName

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Affiliation

Department of Internal Medicine, Faculty of Medicine, Zagazig University, Sharkia, Egypt

Email

saidabdelbaky12345@gmail.com

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Orcid

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Volume

80

Article Issue

3

Related Issue

15828

Issue Date

2020-07-01

Receive Date

2020-08-02

Publish Date

2020-07-01

Page Start

1,003

Page End

1,007

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 80_Issue 3_Pages 1003-1007.pdf

PDF . 379.6kB

Link

https://ejhm.journals.ekb.eg/article_106016.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=106016

Order

9

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Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Renal Impairment and Nonalcoholic Fatty Liver Disease. Disease – Disease Relationship

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Type

Article

Created At

22 Jan 2023