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103582

Albumin and Magnetic Resonance Imaging-Liver Volume to Identify Hepatitis C-related Cirrhosis and Esophageal Varices

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Last updated: 03 Jan 2025

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Abstract

Background: Liver cirrhosis is the 3rd leading cause of death globally, with increasing mortality rate worldwide portal hypertension is a frequent consequence in the progress of liver cirrhosis and plays a crucial role in the progression of the disease. One of the most serious complications of portal hypertension is the development of esophageal varices. Objective: To evaluate the changes in the liver lobes volume with that of albumin as non-invasive predictors of liver cirrhosis and esophageal varices. Patients and methods: One hundred cases are chosen and classified into four groups as 20 healthy as controls, 20 cases HCV without cirrhosis, 40 cases with cirrhosis but without varices, and 20 cirrhotic cases with varices. All participants undergo magnetic resonance imaging for liver lobes volume, biochemical analysis of serum albumin. All cirrhotic patients are exposed to upper gastro-intestinal endoscopy to differentiate cirrhotic with or without varices. Statistical analysis was done to determine the combination of liver lobes volume change together with albumin changes to predict the severity of cirrhosis and for esophageal varices.
Results: RV, LMV, LLV, and albumin are significantly lower in cases of cirrhosis and LMV/albumin LLV/ALB, CV/Albumin shows a more significant difference in cirrhotics with varices.
Conclusion: From the results of our study we conclude that MRI liver lobes volume and albumin are good predictors noninvasive markers of liver cirrhosis.

DOI

10.21608/ejhm.2020.103582

Keywords

Liver cirrhosis, serum albumin, MRI

Authors

First Name

Said Abd Elbaky Gad

Last Name

Shams El Deen

MiddleName

-

Affiliation

Department of Internal Medicine, Faculty of Medicine, Zagazig University, Sharkia, Egypt

Email

saidabdelbaky12345@gmail.com

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Orcid

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Volume

80

Article Issue

2

Related Issue

14648

Issue Date

2020-07-01

Receive Date

2020-07-18

Publish Date

2020-07-01

Page Start

899

Page End

906

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 80_Issue 2_Pages 899-906.pdf

PDF . 492.7kB

Link

https://ejhm.journals.ekb.eg/article_103582.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=103582

Order

23

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Albumin and Magnetic Resonance Imaging-Liver Volume to Identify Hepatitis C-related Cirrhosis and Esophageal Varices

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Article

Created At

22 Jan 2023