Background: Renal resistive index (RRI) is markedly affected by renal and systemic conditions. Aortic stiffness with affected pulse pressure in type 2 diabetic patients is associated with backward overload effect on the heart. This had led to consider RRI as a preferred marker for prediction of an increased total cardiovascular risk. Aim: This study interested in detecting the relationship between the renal resistive index and the cardiac diastolic dysfunction in individuals with type 2 diabetes. Patients and methods: A hospital based, cross-sectional study was conducted on 79 type 2 diabetic patients with no symptoms of cardiovascular involvement. They were subjected to echocardiographic evaluation of diastolic dysfunction and renal duplex for measurement of RRI. Results: The results of the current study revealed a significant relationship between renal resistive index and diastolic dysfunction (p < 0.001). Conclusion: Worsening indices of diastolic function in subjects with type 2 diabetes paralleled increases in RRI, which was detected as one of the independent predictors of diastolic dysfunction in these results.