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72544

Effect of Weight Bearing Exercises on Osteoporosis in Prostate Cancer Patients Undergoing Androgen Deprivation Therapy

Article

Last updated: 30 Jan 2023

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Abstract

Background: Most men diagnosed with prostate cancer (PCa) are aged 50 years old or more treated by androgen deprivation therapy (ADT) treatment has been associated with interconnected adverse effects as decreased bone mineral density (BMD) and a loss in the structure and strength of bone leading to osteoporosis. Exercise has been proposed as a treatment to mitigate side effects of ADT. Objective: This study was conducted to evaluate the effect of weight bearing exercises on osteoporosis in prostate cancer patients undergoing androgen deprivation therapy. Patients and methods: The current study was conducted during a period of 3 months starting from 1st October 2019 till 31st December 2019.Thirty PCa patients who had osteoporosis induced by ADT were participated in this study, their ages were over 50 years old. They were selected from the Oncology Hospital Menoufia University and randomly distributed into two equal groups, group A: included 15 patients who received 30 minutes of weight bearing exercises through walking on treadmill, in addition to conventional medical care 3 days /week and group B: included 15 patients who on their conventional medical care. Results: Our study showed that there was a statistically significant improvement in BMD and T-score mean of spine, femoral neck and total femur post treatment compared to that pre-treatment in the group A and B. Conclusion: It can be concluded that weight bearing exercises had fruitful effects in cases of osteoporosis in prostate cancer patients undergoing androgen deprivation therapy as evidenced by the significant increase in BMD and T-score mean.

DOI

10.21608/ejhm.2020.72544

Keywords

Prostate Cancer, Osteoporosis, Androgen Deprivation Therapy, Weight Bearing Exercises, Bone Mineral Density

Authors

First Name

Amr El Sayed

Last Name

El Azizy

MiddleName

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Affiliation

Department of Physical Therapy for Surgery, Faculty of Physical Therapy, Cairo University, Giza, Egypt

Email

amr_elazizy@yahoo.com

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Orcid

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First Name

Emad Tawfik

Last Name

Ahmed

MiddleName

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Affiliation

Department of Physical Therapy for Surgery, Faculty of Physical Therapy, Cairo University, Giza, Egypt

Email

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City

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Orcid

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First Name

Naser

Last Name

Abd Elbary

MiddleName

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Affiliation

Clinical Oncology Department, Faculty of Medicine, Menoufia University, Menoufia, Egypt

Email

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City

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Orcid

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First Name

Hussein Gamal Hussein

Last Name

Mogahed

MiddleName

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Affiliation

Department of Physical Therapy for Surgery, Faculty of Physical Therapy, Cairo University, Giza, Egypt

Email

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City

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Orcid

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Volume

78

Article Issue

2

Related Issue

10587

Issue Date

2020-01-01

Receive Date

2020-02-20

Publish Date

2020-01-01

Page Start

298

Page End

302

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_72544.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=72544

Order

13

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

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Article

Created At

22 Jan 2023