Objective: To assess and to look at serum levels of calcium, magnesium, uric acid and C-reactive protein in mild, extreme preeclamptic ladies and ordinary pregnant ladies and to connect these levels with seriousness of the ailment. Methods: This investigation was a planned observational case-control study that was led at the division of Obstetrics and Gynecology, Al-Azhar University, Maternity Hospital on 90 pregnant ladies in the third trimester of pregnancy (gestational age from 28 to 40 weeks of pregnancy) chosen from the individuals who had gone to the antenatal facility and the banquet hall in the period from January 2018 to June 2019. They were divided into 3 groups: 30 patients with serious preeclampsia, 30 patients with gentle preeclampsia and 30 normotensive ladies free of any medicinal issue (control group). The study was approved by the medical ethics committee of Al-Azhar University Hospitals and a written informed consent is obtained from all participants. Results: The mean estimations of CRP and serum uric acid were fundamentally higher in the pregnant ladies with preeclampsia than in the sound control ladies (p<0.05), while the mean estimations of serum calcium were altogether lower in the pregnant ladies with preeclampsia than in the solid control ladies (p<0.05). The mean serum magnesium didn't demonstrate critical contrasts among preeclampsia and solid ladies (p>0.05). Conclusion: These discoveries bolster the speculation that hypocalcaemia, hyperuricemia and expanded C-reactive protein could be potential etiologies of preeclampsia and that they relate to the seriousness of the illness.