Background: The right ventricle performance is very important in the prognosis of the patients with intracardiac shunts. Development of RV failure is associated with higher mortality. It can be directly related to the shunt itself or indirectly associated with elevated pulmonary artery pressure. Objective: The aim of this work wasto assess the diastolic and the systolic performance of the right ventricle in patients with different types of intracardiac shunts by the Echocardiography in comparison with the normal population. Patients and methods: Our study included 132 patients undergoing echocardiography in the Outpatient Clinic of Tanta University Hospital. The study was conducted starting from 1st of February 2018 to 28th of February 2019. The study included 63 female and 69 male patients. Their age ranged from 1 month to 49 years old. RV diastolic and systolic function were assessed in the four groups using MPI, Stroke work, longitudinal RV strain rate. Results: Our results showed higher values of the parameters measured in the atrial septal defects (ASD) patients' group compared to the normal subjects and the other intracardiac shunt's patients. Also, ASD's patients were associated with higher pulmonary artery pressure values and worse RV function parameters in general. Conclusion: We concluded that the new echocardiographic measures are good and reliable tool to assess the right ventricle function in the patients with intracardiac shunts. Additionally, ASD' patients are associated with worse outcome especially if they develop elevated pulmonary artery pressure.