Background: Intestine anastomosis in pediatric surgery is a relevant matter because of the frequency of the procedure, nonetheless, there is no general agreement about the most appropriate surgical technique, nor are there records comparing the different methods in children. To validate the better technique in children, it is necessary to have clinically comparative experimental studies. Objective: the aim of this work is to evaluate both single layer simple interrupted extramucosal and single layer interrupted Connell sutures for intestinal anastomosis in children in elective and emergency laparotomy as regard technical, functional and financial aspects. Patients and Methods: his study was carried out on 40 patients candidate for intestinal anastomosis in elective and emergency laparotomy managed at Pediatric Surgery Department, Al-Azhar University in Cairo throughout the period from January 2017 to May 2019. Results: As regard the most frequent diagnosis or cause for anastomosis in our study, jejunal atresia was the most common cause of anastomosis with 9 cases (45%) in the extramucosal group and one case (5%) in the Connell group, then the intussusception with 2 patients (10%) in the extramucosal group, and 7 patients (35%) in the Connell group, then ileal atresia, 3 patients (15%) in the extramucosal group, and one patient (5%) in the Connell group. Conclusion: We concluded that both techniques for intestinal anastomosis are effective, safe and successful. We prefer single-layer interrupted extramucosal technique in elective and emergency laparotomy due to less operative time, and valuable cost-effectiveness.