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41913

Bleeding time after magnesium sulphate infusion in cases of preeclampsia

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Last updated: 03 Jan 2025

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Abstract

Background: preeclampsia is a pregnancy-associated multisystem disorder that affects 3-5% of all pregnancies . It remains a leading cause of maternal and neonatal morbidity and mortality in the world . Magnesium sulphate is the drug of choice in the management of impending eclampsia and eclampsia. Magnesium sulphate has an anticoagulating effect, which has been used early in preeclampsia to delay the advance of the disease . This action however, is considered as a disadvantage, because it can prolong the bleeding time.The prolongation of bleeding time may preceipitate postpartum haemorrhage. Objective: the objective of this study was to observe the effects of magnesium sulphate on bleeding time in patients with preeclampsia. Patients and Methods: a study was conducted between April 2018 and February 2019. Fiffty patients with preeclampsia were included in the study. Bleeding time was measured through modified Ivy method. These measures were recorded before, immediately and 24 hours after discontinuation of magnesium sulphate. Results: after magnesium sulphate therapy; bleeding time is increased , haemoglobin level and haematocrit level are decreased. Conclusion: bleeding time in patients with severe preeclampsia was prolonged with magnesium sulphate infusion This is clinically important because it worsens the present conition and causes possible complications.

DOI

10.21608/ejhm.2019.41913

Keywords

C-reactive protein, Gestational diabetes

Authors

First Name

Ismaeil Mohamed Abd El- Azeim

Last Name

Mira

MiddleName

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Affiliation

Departments of Obstetrics & Gynecology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

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Orcid

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First Name

Abd El- Monsef Abd El- Hamed

Last Name

Sedek

MiddleName

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Affiliation

Departments of Obstetrics & Gynecology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

Email

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City

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Orcid

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First Name

Ahmed Fathy

Last Name

Abd EL- Aziz

MiddleName

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Affiliation

Departments of Clinical Pathology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

Email

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City

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Orcid

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First Name

Ahmed Ayman

Last Name

Marey

MiddleName

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Affiliation

Departments of Obstetrics & Gynecology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

Email

hamada_mar3e@yahoo.com

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Orcid

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Volume

76

Article Issue

4

Related Issue

6546

Issue Date

2019-07-01

Receive Date

2019-07-22

Publish Date

2019-07-01

Page Start

3,957

Page End

3,962

Print ISSN

1687-2002

Online ISSN

2090-7125

Link

https://ejhm.journals.ekb.eg/article_41913.html

Detail API

https://ejhm.journals.ekb.eg/service?article_code=41913

Order

18

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Bleeding time after magnesium sulphate infusion in cases of preeclampsia

Details

Type

Article

Created At

22 Jan 2023