Background: Cardiomyopathies (CMPs) are a group of myocardial diseases with adverse outcomes. Aim of the study: Was to evaluate the global and segmental 3–dimensional strain using speckle tracking echocardiography in children with dilated cardiomyopathy and correlate this parameter with other echocardiographic findings especially 2-dimensional strain (2DS bull's eye). Patients and Methods: 100 subjects were categorized into 2 groups: Group 1; 50 patients with dilated cardiomyopathy. Group 2; 50 healthy controls matched with the patient group. Echocardiographic studies were performed by the following: Routine echocardiographic examination, tissue Doppler examination (TDE): [systolic and diastolic mitral annulus velocities - LV myocardial performance Index (MPI)], speckling tracking technique [2D LV longitudinal strain (2DS bull's eye) - Auto EF for LV systolic function - sphericity index] and transthoracic 3DE examination (3DRTE) [3D longitudinal strain (3DS bull's eye)]. Results: There was a significant reduction in left ventricular ejection fraction (LVEF), sphericity index (SI), mitral annulus systolic velocity (S), early diastolic mitral annulus tissue velocity and late diastolic mitral annulus tissue velocity (E'/A') and LV GLS (global longitudinal strain) in patients when compared with controls but there was a significant increase in myocardial performance index (MPI) and 2 dimensional (2DS) than 3 dimensional (3DS) in patients when compared with controls. There was significant positive correlation between 2DS and 3DS GLS among patients also, there was good agreement between all items in 2DS and 3DS in patients group. Conclusion: The bull's eye plot offers an intuitive visual overview of LV myocardial function status in cardiomyopathies.